MetaCyc Pathway: 3-phenylpropanoate degradation in Agrobacterium fabrum C58

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Reactions and Genes L-Lysine (N)
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3-phenylpropanoate + ATP + coenzyme A→3-phenylpropanoyl-CoA + AMP + diphosphate
No genes
3-phenylpropanoyl-CoA + an oxidized electron carrier→(E)-cinnamoyl-CoA + a reduced two electron carrier
No genes
Enoyl-CoA hydratase (in reverse):
(E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA
(EC 4.2.1.17)
Atu0322 -0.8
Atu0503 +0.2
Atu0733 +0.1
Atu1417 +0.1
Atu3481 -0.2
Atu3505 -0.2
3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxy-3-phenylpropanoyl-CoA + NAD+→3-oxo-3-phenylpropanoyl-CoA + NADH + H+
(EC 1.1.1.35)
Atu0503 +0.2
Atu1415 +0.0
Acetyl-CoA C-acyltransferase (in reverse):
3-oxo-3-phenylpropanoyl-CoA + coenzyme A→benzoyl-CoA + acetyl-CoA
(EC 2.3.1.16)
Atu0502 -0.0
Atu2769 -3.0
Atu3475 -0.2
Atu4549 -0.2
Atu4823 -0.3
Benzoyl-CoA 3-monooxygenase:
benzoyl-CoA + NADPH + dioxygen + H+→3-hydroxybenzoyl-CoA + NADP+ + H2O
(EC 1.14.13.58)
No genes
3-hydroxybenzoyl-CoA + a reduced two electron carrier + dioxygen→gentisate + an oxidized electron carrier + coenzyme A + H+
No genes
Gentisate 1,2-dioxygenase:
gentisate + dioxygen→3-maleylpyruvate + H+
(EC 1.13.11.4)
No genes
Maleylpyruvate isomerase:
3-maleylpyruvate→3-fumarylpyruvate
(EC 5.2.1.4)
No genes
3-fumarylpyruvate + H2O→fumarate + pyruvate + H+ (EC 3.7.1.20)
Atu1516 +0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information