MetaCyc Pathway: biotin-carboxyl carrier protein assembly in Pseudomonas simiae WCS417

Reactions and Genes	Gentamicin 0.008 mg/ml
Biotin--[acetyl-CoA-carboxylase] ligase: a [biotin carboxyl-carrier protein]-L-lysine + ATP + biotin→a [biotin carboxyl-carrier protein]-N6-biotinyl-L-lysine + AMP + diphosphate + H+ (EC 6.3.4.15)
PS417_25635	-1.8
2 a [biotin carboxyl-carrier protein]-N6-biotinyl-L-lysine→a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine (spontaneous)
No genes
Biotin carboxylase: a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + ATP + hydrogen carbonate→a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + ADP + H+ + phosphate (EC 6.3.4.14)
PS417_25350	-0.0
PS417_02965	N.D.
PS417_02970	N.D.
a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine + acetyl-CoA→a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine + malonyl-CoA (EC 2.1.3.15)
PS417_06290	N.D.
PS417_18555	N.D.

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information