MetaCyc Pathway: NAD(P)/NADPH interconversion in Escherichia coli BW25113
| Reactions and Genes | deuterated glucose in D2O |
|---|---|
| remove | |
| NAD(+) kinase: NAD+ + ATP→NADP+ + ADP + H+ (EC 2.7.1.23; 2.7.1.M29) | |
| b2615 (yfjB) | N.D. |
| NADP+ + H2O→NAD+ + phosphate (EC 3.1.3.108) | |
| b0383 (phoA) | -0.0 |
| NAD+[in] + 4 H+[out] + a ubiquinol→NADH[in] + 5 H+[in] + a ubiquinone (EC 7.1.1.2) | |
| b1109 (ndh) | -0.1 |
| b2276 (nuoN) | +0.3 |
| b2277 (nuoM) | +0.2 |
| b2278 (nuoL) | +0.1 |
| b2279 (nuoK) | +0.5 |
| b2280 (nuoJ) | +0.3 |
| b2282 (nuoH) | +0.4 |
| b2283 (nuoG) | +0.4 |
| b2284 (nuoF) | +0.3 |
| b2285 (nuoE) | +0.3 |
| b2286 (nuoC) | +0.4 |
| b2287 (nuoB) | +0.4 |
| b2288 (nuoA) | +0.0 |
| NAD(P)(+) transhydrogenase (B-specific): NAD+ + NADPH→NADH + NADP+ (EC 1.6.1.1; 1.6.1.3) | |
| b1602 (pntB) | -0.7 |
| b1603 (pntA) | -1.3 |
| b3962 (udhA) | -0.2 |
| NADH kinase: NADH + ATP→NADPH + ADP + H+ (EC 2.7.1.86; 2.7.1.M29) | |
| No genes | |
| NADPH + H2O→NADH + phosphate (EC 3.1.3.108) | |
| No genes | |
Links:
- Pathway details at MetaCyc
- Fitness data for 18 genes
- All MetaCyc pathways for Escherichia coli BW25113
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information