MetaCyc Pathway: L-glutamate and L-glutamine biosynthesis in Agrobacterium fabrum C58

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Reactions and Genes Ethanolamine (N)
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Glutamate dehydrogenase (NAD(P)(+)) (in reverse):
2-oxoglutarate + ammonium + NAD(P)H + H+→L-glutamate + NAD(P)+ + H2O (EC 1.4.1.3)
No genes
Glutamate synthase (ferredoxin) (in reverse):
2-oxoglutarate + L-glutamine + 2 H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→2 L-glutamate + 2 an oxidized ferredoxin [iron-sulfur] cluster (EC 1.4.7.1)
No genes
Glutamate synthase (NADH) (in reverse):
2-oxoglutarate + L-glutamine + NADH + H+→2 L-glutamate + NAD+ (EC 1.4.1.14)
Atu0145 -0.0
Atu3783 -1.9
Glutamate synthase (NADPH):
L-glutamine + H2O→L-glutamate + ammonia + H+ (EC 1.4.1.13; 1.4.1.14; 1.4.7.1; 2.6.1.85; 3.5.1.2; 3.5.1.38; 4.1.3.27; 4.3.2.10; 4.3.3.6; 6.3.4.2; 6.3.5.13; 6.3.5.2; 6.3.5.4; 6.3.5.5; 6.3.5.6; 6.3.5.7)
Atu0145 -0.0
Atu0281 N.D.
Atu0930 -0.1
Atu1154 -0.1
Atu1318 N.D.
Atu1319 N.D.
Atu1324 N.D.
Atu1618 N.D.
Atu1676 -0.0
Atu1859 +0.0
Atu2170 N.D.
Atu2178 N.D.
Atu2289 -3.8
Atu2658 -0.0
Atu3243 +0.1
Atu3369 -0.5
Atu3640 +0.1
Atu3783 -1.9
Atu3784 -1.9
Atu4228 -0.2
Atu4229 -0.1
Atu4441 +0.0
Atu4443 +0.1
Atu5476 -0.0
Glutamate--ammonia ligase:
L-glutamate + ammonium + ATP→L-glutamine + ADP + H+ + phosphate (EC 6.3.1.2)
Atu0193 -0.1
Atu0602 -0.0
Atu1770 -0.4
Atu2142 -2.5
Atu2416 -0.8
Atu4230 +0.0
Glutamate dehydrogenase (NADP(+)) (in reverse):
2-oxoglutarate + ammonium + NADPH + H+→L-glutamate + NADP+ + H2O (EC 1.4.1.4)
No genes
Glutamate synthase (NADPH) (in reverse):
2-oxoglutarate + ammonia + NADPH + 2 H+→L-glutamate + NADP+ + H2O (EC 1.4.1.13; 1.4.1.14)
Atu0145 -0.0
Atu0930 -0.1
Atu1154 -0.1
Atu3640 +0.1
Atu3783 -1.9
Atu3784 -1.9
Atu4228 -0.2
Atu4229 -0.1
Atu4443 +0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information