MetaCyc Pathway: fatty acid β-oxidation I (generic) in Pseudomonas simiae WCS417

Add experiment(s):


Reactions and Genes L-Valine (C)
remove
a 2,3,4-saturated fatty acid + ATP + coenzyme A→a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate
No genes
Dodecenoyl-CoA isomerase:
a (3Z)-3-enoyl-CoA→a (2E)-2-enoyl-CoA
(EC 5.3.3.8)
PS417_07575 -0.6
3-hydroxybutyryl-CoA epimerase:
a 2,3,4-saturated (3R)-3-hydroxyacyl-CoA→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA
(EC 5.1.2.3)
PS417_07575 -0.6
PS417_21215 -0.2
a 2,3,4-saturated fatty acyl CoA + an oxidized electron-transfer flavoprotein + H+→a (2E)-2-enoyl-CoA + a reduced electron-transfer flavoprotein
No genes
Enoyl-CoA hydratase (in reverse):
a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA
(EC 4.2.1.17)
PS417_07030 -0.3
PS417_07575 -0.6
PS417_08535 -0.5
PS417_10680 -0.6
PS417_11445 -0.4
PS417_12870 +0.1
PS417_13835 -4.1
PS417_13845 N.D.
PS417_21195 +0.8
PS417_21215 -0.2
PS417_22625 +0.2
3-hydroxyacyl-CoA dehydrogenase:
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+→a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+
(EC 1.1.1.35)
PS417_07575 -0.6
PS417_21215 -0.2
PS417_26285 -0.3
Acetyl-CoA C-acyltransferase (in reverse):
a 2,3,4-saturated 3-oxoacyl-CoA + coenzyme A→a 2,3,4-saturated fatty acyl CoA + acetyl-CoA
(EC 2.3.1.16)
PS417_06710 -2.4
PS417_07580 N.D.
PS417_10515 +0.0
PS417_13855 -1.1
PS417_15175 N.D.
PS417_19210 +0.4
PS417_21220 +0.1
PS417_03145 -0.4

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information