| Reactions and Genes | Hippuric (N) |
|---|
| remove |
| a 2,3,4-saturated fatty acid + ATP + coenzyme A→a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate |
| No genes |
Acyl-CoA oxidase:
a 2,3,4-saturated fatty acyl CoA + dioxygen→a (2E)-2-enoyl-CoA + hydrogen peroxide (EC 1.3.3.6) |
| No genes |
Enoyl-CoA hydratase (in reverse):
a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA (EC 4.2.1.17) |
| PP_1412 | +0.2 |
| PP_1845 | -0.4 |
| PP_2047 | +0.1 |
| PP_2136 | -1.3 |
| PP_2217 | +0.4 |
| PP_3283 | +0.1 |
| PP_3284 | -0.0 |
| PP_3358 | +0.0 |
| PP_3491 | -0.0 |
| PP_3726 | -0.5 |
| PP_3732 | +0.4 |
| PP_4030 | -0.4 |
| a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3R)-3-hydroxyacyl-CoA (EC 4.2.1.119) |
| PP_4552 | N.D. |
3-hydroxyacyl-CoA dehydrogenase:
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+→a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+ (EC 1.1.1.35) |
| PP_2047 | +0.1 |
| PP_2136 | -1.3 |
| a 2,3,4-saturated (3R)-3-hydroxyacyl-CoA + NAD+→a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+ (EC 1.1.1.M19) |
| No genes |
Acetyl-CoA C-acyltransferase (in reverse):
a 2,3,4-saturated 3-oxoacyl-CoA + coenzyme A→a 2,3,4-saturated fatty acyl CoA + acetyl-CoA (EC 2.3.1.16) |
| PP_0582 | +0.1 |
| PP_1377 | -3.1 |
| PP_2051 | -0.1 |
| PP_2137 | -0.4 |
| PP_2215 | +0.2 |
| PP_3280 | +0.4 |
| PP_3355 | +0.0 |
| PP_3754 | -0.4 |
| PP_4636 | -0.3 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information