MetaCyc Pathway: ketolysis in Pseudomonas putida KT2440

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Reactions and Genes Hippuric (N)
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3-hydroxybutyrate dehydrogenase:
(R)-3-hydroxybutanoate + NAD+→acetoacetate + NADH + H+
(EC 1.1.1.30)
PP_2784 +0.2
PP_3073 -0.4
3-oxoacid CoA-transferase:
acetoacetate + succinyl-CoA→acetoacetyl-CoA + succinate
(EC 2.8.3.5)
PP_3122 +0.1
PP_3123 -0.1
Acetyl-CoA C-acyltransferase (in reverse):
acetoacetyl-CoA + coenzyme A→2 acetyl-CoA
(EC 2.3.1.16; 2.3.1.9)
PP_0582 +0.1
PP_1377 -3.1
PP_2051 -0.1
PP_2137 -0.4
PP_2215 +0.2
PP_3280 +0.4
PP_3355 +0.0
PP_3754 -0.4
PP_4636 -0.3

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information