MetaCyc Pathway: superpathway of L-aspartate and L-asparagine biosynthesis in Pseudomonas putida KT2440

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Reactions and Genes R2A control with 0.2% methanol
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Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→L-aspartate + 2-oxoglutarate
(EC 2.6.1.1)
PP_0486 -0.1
PP_0858 -0.1
PP_1109 +0.7
PP_1872 -0.1
PP_2642 +0.2
PP_2948 -0.0
PP_3544 -0.1
PP_3750 -0.1
PP_3786 +0.1
PP_4197 +1.3
PP_5275 -0.2
PP_5342 -0.0
Aspartate ammonia-lyase (in reverse):
fumarate + ammonium→L-aspartate
(EC 4.3.1.1)
PP_5338 -0.1
Aspartate--ammonia ligase:
L-aspartate + ammonium + ATP→L-asparagine + AMP + diphosphate + H+
(EC 6.3.1.1)
No genes
Asparaginase:
L-asparagine + H2O→L-aspartate + ammonium
(EC 3.5.1.1; 3.5.1.38; 3.5.5.4)
PP_0495 -0.1
PP_1160 +0.2
PP_2453 -0.3

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information