MetaCyc Pathway: lactose degradation I in Escherichia coli ECOR38

Reactions and Genes	Sodium-DL-Lactate
	remove
lactose_[out] + an [HPr protein]-N^π-phospho-L-histidine_[in]→lactose 6'-phosphate_[in] + an [HPr]-L-histidine_[in] (EC 2.7.1.207)
No genes
6-phospho-beta-galactosidase: lactose 6'-phosphate + H₂O→D-galactopyranose 6-phosphate + D-glucopyranose (EC 3.2.1.85)
No genes
Galactose-6-phosphate isomerase: D-galactopyranose 6-phosphate→D-tagatofuranose 6-phosphate (EC 5.3.1.26)
No genes
Tagatose-6-phosphate kinase: D-tagatofuranose 6-phosphate + ATP→D-tagatofuranose 1,6-bisphosphate + ADP + H⁺ (EC 2.7.1.144)
HEPCGN_02800 (gatZ)	-0.3
HEPCGN_05400 (pfkB)	+0.0
HEPCGN_12475 (pfkA)	+0.4
HEPCGN_17170 (kbaZ)	+0.1
HEPCGN_22705 (fruB)	-6.0
Tagatose-bisphosphate aldolase: D-tagatofuranose 1,6-bisphosphate→glycerone phosphate + D-glyceraldehyde 3-phosphate (EC 4.1.2.40)
HEPCGN_02795 (gatY)	-0.0
HEPCGN_02800 (gatZ)	-0.3
HEPCGN_14330	-0.1
HEPCGN_14335 (fba)	-0.1
HEPCGN_15410 (fba)	-0.1
HEPCGN_16535 (gatY)	+0.1
HEPCGN_17135 (kbaY)	-0.2
HEPCGN_17170 (kbaZ)	+0.1

Links:

Pathway details at MetaCyc
Fitness data for 11 genes
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All MetaCyc pathways for Escherichia coli ECOR38

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information