MetaCyc Pathway: superpathway of glucose and xylose degradation in Hydrogenophaga sp. GW460-11-11-14-LB1

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Reactions and Genes Ying_all64 rep C; time point 3
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Glucose-6-phosphate dehydrogenase:
D-glucopyranose 6-phosphate + NADP+→6-phospho D-glucono-1,5-lactone + NADPH + H+ (EC 1.1.1.49)
GFF5493 +1.5
Xylose isomerase:
α-D-xylopyranose→α-D-xylulofuranose (EC 5.3.1.5)
No genes
6-phosphogluconolactonase:
6-phospho D-glucono-1,5-lactone + H2O→D-gluconate 6-phosphate + H+ (EC 3.1.1.31)
GFF5494 N.D.
Xylulokinase:
D-xylulose + ATP→D-xylulose 5-phosphate + ADP + H+ (EC 2.7.1.17)
GFF4370 +0.0
Phosphogluconate dehydrogenase (decarboxylating):
D-gluconate 6-phosphate + NADP+→D-ribulose 5-phosphate + CO2 + NADPH (EC 1.1.1.44)
No genes
Ribose-5-phosphate isomerase (in reverse):
D-ribulose 5-phosphate→D-ribose 5-phosphate (EC 5.3.1.6)
GFF4212 N.D.
Ribulose-phosphate 3-epimerase:
D-ribulose 5-phosphate→D-xylulose 5-phosphate (EC 5.1.3.1)
GFF2197 +0.7
GFF3096 N.D.
Transketolase (in reverse):
D-ribose 5-phosphate + D-xylulose 5-phosphate→D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (EC 2.2.1.1)
GFF2200 +0.4
GFF2487 N.D.
Transaldolase:
D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate→D-erythrose 4-phosphate + β-D-fructofuranose 6-phosphate (EC 2.2.1.2)
GFF1363 +0.0
Transketolase:
D-erythrose 4-phosphate + D-xylulose 5-phosphate→β-D-fructofuranose 6-phosphate + D-glyceraldehyde 3-phosphate (EC 2.2.1.1)
GFF2200 +0.4
GFF2487 N.D.
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+ (EC 1.2.1.12)
GFF1114 -0.5
GFF2202 N.D.
GFF2203 N.D.
GFF2488 N.D.
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP (EC 2.7.2.3)
GFF2204 N.D.
GFF2205 N.D.
GFF2581 N.D.
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
GFF1226 N.D.
GFF1661 N.D.
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
GFF5442 N.D.
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
GFF2780 +2.1
D-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(R)-lactate + NAD+ (EC 1.1.1.28)
No genes
L-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(S)-lactate + NAD+ (EC 1.1.1.27)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information