| Reactions and Genes | Ying_all64 rep C; time point 3 |
|---|
| remove |
Vanillin dehydrogenase:
vanillin + NAD+ + H2O→vanillate + NADH + 2 H+ (EC 1.2.1.67) |
| GFF2629 | +0.5 |
| vanillate + a tetrahydrofolate→protocatechuate + a 5-methyltetrahydrofolate (EC 2.1.1.341) |
| No genes |
Protocatechuate 4,5-dioxygenase:
protocatechuate + dioxygen→4-carboxy-2-hydroxymuconate-6-semialdehyde + H+ (EC 1.13.11.8) |
| GFF1652 | -0.1 |
| GFF1653 | -0.0 |
| GFF3312 | +0.5 |
| GFF3801 | -1.7 |
| GFF3802 | -0.8 |
| 4-carboxy-2-hydroxymuconate-6-semialdehyde→2-hydroxy-4-carboxymuconate semialdehyde hemiacetal (spontaneous) |
| No genes |
| 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal + NADP+→2-pyrone-4,6-dicarboxylate + NADPH + H+ (EC 1.1.1.312) |
| GFF3803 | -4.1 |
2-pyrone-4,6-dicarboxylate lactonase:
2-pyrone-4,6-dicarboxylate + H2O→(1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + H+ (EC 3.1.1.57) |
| GFF3800 | +0.4 |
| (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate→(1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate (spontaneous) (EC 5.3.2.8) |
| No genes |
4-oxalmesaconate hydratase (in reverse):
(1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate + H2O→2-hydroxy-4-oxobutane-1,2,4-tricarboxylate (EC 4.2.1.83) |
| GFF3798 | -0.9 |
4-hydroxy-4-methyl-2-oxoglutarate aldolase:
2-hydroxy-4-oxobutane-1,2,4-tricarboxylate→oxaloacetate + pyruvate (EC 4.1.3.17) |
| GFF2963 | +0.1 |
| GFF3799 | -0.9 |
| GFF5061 | N.D. |
Malate dehydrogenase (oxaloacetate-decarboxylating):
oxaloacetate + H+→pyruvate + CO2 (EC 1.1.1.38; 1.1.1.40; 1.1.1.83; 4.1.1.112) |
| GFF2469 | +1.7 |
| GFF2675 | -0.9 |
| GFF3306 | -0.3 |
| GFF3799 | -0.9 |
| GFF3852 | -0.8 |
| GFF5061 | N.D. |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information