MetaCyc Pathway: mixed acid fermentation in Variovorax sp. OAS795

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Reactions and Genes D-Mannose (C)
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Phosphoenolpyruvate carboxylase (in reverse):
phosphoenolpyruvate + hydrogen carbonate→oxaloacetate + phosphate (EC 4.1.1.31)
ABID97_RS08220 -5.1
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
ABID97_RS01755 -2.1
ABID97_RS24455 +0.2
ABID97_RS27675 +0.6
D-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(R)-lactate + NAD+ (EC 1.1.1.28)
No genes
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
ABID97_RS05795 -2.3
ABID97_RS08515 N.D.
ABID97_RS17295 +0.0
Formate C-acetyltransferase (in reverse):
pyruvate + coenzyme A→acetyl-CoA + formate (EC 2.3.1.54)
No genes
Acetaldehyde dehydrogenase (acetylating) (in reverse):
acetyl-CoA + NADH + H+→acetaldehyde + coenzyme A + NAD+ (EC 1.2.1.10)
ABID97_RS27925 -0.0
Citrate (Si)-synthase:
acetyl-CoA + oxaloacetate + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16; 2.3.3.3)
ABID97_RS01110 +0.5
ABID97_RS01120 +0.4
ABID97_RS07945 +0.3
ABID97_RS08480 -1.9
ABID97_RS26895 -0.5
ABID97_RS28890 +0.2
formate + H+→CO2 + H2
No genes
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
ABID97_RS17545 +0.3
ABID97_RS17550 -0.1
Phosphate acetyltransferase:
acetyl-CoA + phosphate→acetyl phosphate + coenzyme A (EC 2.3.1.8)
ABID97_RS21830 N.D.
Acetate kinase (in reverse):
acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15)
ABID97_RS00805 +0.0
ABID97_RS21845 +0.5
Aconitate hydratase:
citrate→cis-aconitate + H2O (EC 4.2.1.3)
ABID97_RS08535 N.D.
ABID97_RS08550 +0.3
Alcohol dehydrogenase (in reverse):
acetaldehyde + NADH + H+→ethanol + NAD+ (EC 1.1.1.1)
ABID97_RS10235 +0.0
ABID97_RS13195 -0.2
ABID97_RS13275 +0.0
ABID97_RS15955 -0.0
ABID97_RS18840 +0.1
ABID97_RS25565 +0.0
ABID97_RS27980 +0.4
ABID97_RS29150 -0.8
ABID97_RS29360 +0.2
Succinate dehydrogenase (ubiquinone):
fumarate[in] + a menaquinol→succinate[in] + a menaquinone (EC 1.3.5.1)
No genes
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3)
ABID97_RS08535 N.D.
ABID97_RS08550 +0.3
Isocitrate dehydrogenase (NADP(+)):
D-threo-isocitrate + NADP+→CO2 + 2-oxoglutarate + NADPH (EC 1.1.1.42)
ABID97_RS16920 -1.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information