MetaCyc Pathway: superpathway of glycol metabolism and degradation in Variovorax sp. OAS795

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Reactions and Genes Adenine (C)
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Lactaldehyde reductase:
ethylene glycol + NAD+→glycolaldehyde + NADH + H+ (EC 1.1.1.77)
No genes
Glycolaldehyde dehydrogenase:
glycolaldehyde + NAD+ + H2O→glycolate + NADH + 2 H+ (EC 1.2.1.21)
ABID97_RS13510 +0.1
ABID97_RS13535 +0.3
ABID97_RS15020 -0.3
ABID97_RS18885 +0.1
ABID97_RS25410 N.D.
ABID97_RS25710 N.D.
ABID97_RS25990 -0.6
ABID97_RS28560 N.D.
ABID97_RS29450 -0.1
Glycolate dehydrogenase:
glycolate[in] + an electron-transfer quinone→glyoxylate[in] + an electron-transfer quinol (EC 1.1.99.14)
ABID97_RS03650 +0.4
ABID97_RS03655 +0.7
ABID97_RS03660 +0.4
ABID97_RS15850 +0.2
Tartronate-semialdehyde synthase:
2 glyoxylate + H+→(2R)-tartronate semialdehyde + CO2 (EC 4.1.1.47)
ABID97_RS22320 -4.1
Malate synthase:
glyoxylate + acetyl-CoA + H2O→(S)-malate + coenzyme A + H+ (EC 2.3.3.9)
ABID97_RS04710 +1.0
2-hydroxy-3-oxopropionate reductase (in reverse):
(2R)-tartronate semialdehyde + NAD(P)H + H+→D-glycerate + NAD(P)+ (EC 1.1.1.60)
ABID97_RS00265 -0.4
ABID97_RS01185 +0.0
ABID97_RS22330 -1.2
D-glycerate + ATP→2-phospho-D-glycerate + ADP + H+ (EC 2.7.1.165)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information