MetaCyc Pathway: phosphatidylglycerol biosynthesis I in Escherichia coli BW25113

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Reactions and Genes 1-ethyl-3-methylimidazolium chloride 80 mM
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Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) (in reverse):
glycerone phosphate + NAD(P)H + H+sn-glycerol 3-phosphate + NAD(P)+
(EC 1.1.1.94)
b3608 (gpsA) N.D.
Glycerol-3-phosphate O-acyltransferase:
sn-glycerol 3-phosphate + an acyl-[acyl-carrier protein]→a 2-lysophosphatidate + a soluble [acyl-carrier protein]
(EC 2.3.1.15)
b1090 (plsX) +2.1
b3059 (ygiH) +0.1
b4041 (plsB) +0.8
1-acylglycerol-3-phosphate O-acyltransferase:
a 2-lysophosphatidate + an acyl-[acyl-carrier protein]→a phosphatidate + a soluble [acyl-carrier protein]
(EC 2.3.1.51)
b3018 (plsC) N.D.
b3862 (yihG) -0.1
Phosphatidate cytidylyltransferase:
a phosphatidate + CTP + H+→a CDP-diacylglycerol + diphosphate
(EC 2.7.7.41)
b0175 (cdsA) N.D.
b1409 (ynbB) -1.3
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase:
a CDP-diacylglycerol + sn-glycerol 3-phosphate→a phosphatidylglycerophosphate + CMP + H+
(EC 2.7.8.5)
b1408 (b1408) -0.6
b1912 (pgsA) N.D.
Phosphatidylglycerophosphatase:
a phosphatidylglycerophosphate + H2O→a phosphatidylglycerol + phosphate
(EC 3.1.3.27)
b0418 (pgpA) +1.8
b1278 (pgpB) +1.0
b2560 (yfhB) -0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information