MetaCyc Pathway: L-selenocysteine biosynthesis II (archaea and eukaryotes) in Escherichia coli BW25113

Reactions and Genes	1-ethyl-3-methylimidazolium chloride 80 mM
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Selenide, water dikinase: selenide + ATP + H₂O→selenophosphate + AMP + phosphate (EC 2.7.9.3)
b1764 (selD)	+1.4
Serine--tRNA ligase: L-serine + ATP + a tRNA^sec→an L-seryl-[tRNA^sec] + AMP + diphosphate (EC 6.1.1.11)
b0893 (serS)	N.D.
an L-seryl-[tRNA^sec] + ATP→an O-phospho-L-seryl-[tRNA^Sec] + ADP + H⁺ (EC 2.7.1.164)
No genes
an O-phospho-L-seryl-[tRNA^Sec] + selenophosphate + H₂O→an L-selenocysteinyl-[tRNA^sec] + 2 phosphate (EC 2.9.1.2)
No genes

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Pathway details at MetaCyc
Fitness data for 2 genes
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All MetaCyc pathways for Escherichia coli BW25113

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information