MetaCyc Pathway: pseudouridine degradation in Escherichia coli BW25113
| Reactions and Genes | 1-ethyl-3-methylimidazolium chloride 80 mM |
|---|---|
| remove | |
| Pseudouridine kinase: pseudouridine + ATP→pseudouridine 5'-phosphate + ADP + H+ (EC 2.7.1.83) | |
| b2160 (yeiI) | -0.1 |
| b2166 (yeiC) | -0.3 |
| Pseudouridylate synthase (in reverse): pseudouridine 5'-phosphate + H2O→uracil + D-ribofuranose 5-phosphate (EC 4.2.1.70) | |
| b0058 (rluA) | +0.1 |
| b1086 (rluC) | -0.2 |
| b1135 (ymfC) | -0.4 |
| b1269 (rluB) | -0.1 |
| b2165 (yeiN) | -0.1 |
| b2183 (rsuA) | -0.8 |
| b2318 (truA) | -0.7 |
| b2594 (rluD) | N.D. |
| b2791 (yqcB) | +0.1 |
| b3166 (truB) | -1.6 |
| b4022 (yjbC) | +0.2 |
Links:
- Pathway details at MetaCyc
- Fitness data for 13 genes
- All MetaCyc pathways for Escherichia coli BW25113
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information