MetaCyc Pathway: cardiolipin biosynthesis II in Escherichia coli BW25113

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Reactions and Genes 1-ethyl-3-methylimidazolium chloride 80 mM
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CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase:
a CDP-diacylglycerol + sn-glycerol 3-phosphate→a phosphatidylglycerophosphate + CMP + H+ (EC 2.7.8.5)
b1408 (b1408) -0.6
b1912 (pgsA) N.D.
Phosphatidylglycerophosphatase:
a phosphatidylglycerophosphate + H2O→a phosphatidylglycerol + phosphate (EC 3.1.3.27)
b0418 (pgpA) +1.8
b1278 (pgpB) +1.0
b2560 (yfhB) -0.0
a CDP-diacylglycerol + a phosphatidylglycerol→a cardiolipin + CMP + H+ (EC 2.7.8.41)
b0789 (ybhO) -0.3
b1046 (ymdC) +0.1
b1249 (cls) -2.3

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information