MetaCyc Pathway: superpathway of fatty acid biosynthesis I (E. coli) in Agrobacterium fabrum C58

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Reactions and Genes Betanin (C)
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[Acyl-carrier-protein] S-acetyltransferase:
acetyl-CoA + a soluble [acyl-carrier protein]→an acetyl-[acp] + coenzyme A (EC 2.3.1.38)
No genes
acetyl-CoA + a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine→malonyl-CoA + a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine (EC 2.1.3.15)
Atu0020 N.D.
Atu3630 N.D.
[Acyl-carrier-protein] S-malonyltransferase:
malonyl-CoA + a soluble [acyl-carrier protein]→a malonyl-[acp] + coenzyme A (EC 2.3.1.39)
Atu1094 N.D.
Atu3672 -0.0
Atu3681 -0.1
Atu3683 -0.0
Beta-ketoacyl-acyl-carrier-protein synthase III:
acetyl-CoA + a malonyl-[acp] + H+→an acetoacetyl-[acp] + CO2 + coenzyme A (EC 2.3.1.180)
Atu1179 N.D.
Atu4001 -1.0
Beta-ketoacyl-acyl-carrier-protein synthase II:
an acetyl-[acp] + a malonyl-[acp] + H+→an acetoacetyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
Atu0150 N.D.
Atu1097 N.D.
Atu1596 N.D.
Atu1597 N.D.
Atu4216 -0.0
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxoacyl-[acyl-carrier protein] + NADPH + H+→a (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ (EC 1.1.1.100)
Atu0705 +0.2
Atu0990 -0.0
Atu1095 N.D.
Atu1255 +0.1
Atu1338 +0.0
Atu2042 -0.2
Atu3051 +0.3
Atu3074 -0.0
Atu3333 +0.1
Atu3531 +0.2
Atu3813 -0.1
Atu4220 +0.2
Atu4325 +0.2
Atu4595 -0.0
Atu4821 +0.2
Atu4877 +1.3
Atu5122 -0.3
Atu5214 N.D.
Atu5250 N.D.
Atu5438 -0.2
Atu5465 -0.1
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxyacyl-[acyl-carrier protein]→a trans-2-enoyl-[acyl-carrier protein] + H2O (EC 4.2.1.59)
Atu0151 N.D.
Atu1383 N.D.
Atu1599 N.D.
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxydecanoyl-[acp]→a (2E)-dec-2-enoyl-[acp] + H2O (EC 4.2.1.59)
Atu0151 N.D.
Atu1383 N.D.
Atu1599 N.D.
Trans-2-decenoyl-[acyl-carrier-protein] isomerase:
a (2E)-dec-2-enoyl-[acp]→a (3Z)-dec-3-enoyl-[acp] (EC 5.3.3.14)
Atu0151 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a trans-2-enoyl-[acyl-carrier protein] + NADH + H+→a 2,3,4-saturated fatty acyl-[acp] + NAD+ (EC 1.3.1.9)
Atu0149 -0.7
Atu0757 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) (in reverse):
a trans-2-enoyl-[acyl-carrier protein] + NADPH + H+→a 2,3,4-saturated fatty acyl-[acp] + NADP+ (EC 1.3.1.10; 1.3.1.104; 1.3.1.39)
Atu5181 -0.0
Atu5185 +0.1
Atu5391 N.D.
Beta-ketoacyl-acyl-carrier-protein synthase II:
a 2,3,4-saturated fatty acyl-[acp] + a malonyl-[acp] + H+→a 3-oxoacyl-[acyl-carrier protein] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
Atu0150 N.D.
Atu1097 N.D.
Atu1596 N.D.
Atu1597 N.D.
Atu4216 -0.0
Beta-ketoacyl-acyl-carrier-protein synthase II:
a (3Z)-dec-3-enoyl-[acp] + a malonyl-[acp] + H+→a (5Z)-3-oxododec-5-enoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
Atu0150 N.D.
Atu1097 N.D.
Atu1596 N.D.
Atu1597 N.D.
Atu4216 -0.0
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a (5Z)-3-oxododec-5-enoyl-[acp] + NADPH + H+→a (3R,5Z)-3-hydroxydodec-5-enoyl-[acp] + NADP+ (EC 1.1.1.100)
Atu0705 +0.2
Atu0990 -0.0
Atu1095 N.D.
Atu1255 +0.1
Atu1338 +0.0
Atu2042 -0.2
Atu3051 +0.3
Atu3074 -0.0
Atu3333 +0.1
Atu3531 +0.2
Atu3813 -0.1
Atu4220 +0.2
Atu4325 +0.2
Atu4595 -0.0
Atu4821 +0.2
Atu4877 +1.3
Atu5122 -0.3
Atu5214 N.D.
Atu5250 N.D.
Atu5438 -0.2
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R,5Z)-3-hydroxydodec-5-enoyl-[acp]→a (2E,5Z)-dodeca-3,5-dienoyl-[acp] + H2O (EC 4.2.1.59)
Atu0151 N.D.
Atu1383 N.D.
Atu1599 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E,5Z)-dodeca-3,5-dienoyl-[acp] + NADH + H+→a (5Z)-dodec-5-enoyl-[acp] + NAD+ (EC 1.3.1.9)
Atu0149 -0.7
Atu0757 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information