MetaCyc Pathway: L-tryptophan degradation XIII (reductive Stickland reaction) in Pseudomonas fluorescens GW456-L13

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Reactions and Genes L-Phenylalanine (C)
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Aspartate transaminase:
L-tryptophan + 2-oxoglutarate→(indol-3-yl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27)
PfGW456L13_2059 +0.2
PfGW456L13_2142 -0.7
PfGW456L13_2252 -0.1
PfGW456L13_2943 +0.0
PfGW456L13_2947 +0.3
PfGW456L13_3163 +0.0
PfGW456L13_3206 +0.2
PfGW456L13_3261 +0.1
PfGW456L13_3292 +0.2
PfGW456L13_3363 +0.2
PfGW456L13_4175 +0.1
PfGW456L13_4396 -1.7
PfGW456L13_4856 -0.1
PfGW456L13_4919 +0.1
PfGW456L13_4930 +0.3
PfGW456L13_733 -0.1
PfGW456L13_807 -0.1
Indolelactate dehydrogenase (in reverse):
(indol-3-yl)pyruvate + NADH + H+→(R)-3-(indol-3-yl)lactate + NAD+ (EC 1.1.1.110)
No genes
Cinnamoyl-CoA:phenyllactate CoA-transferase:
(R)-3-(indol-3-yl)lactate + 3-(indol-3-yl)acryloyl-CoA→3-(indol-3-yl)acrylate + (R)-3-(indol-3-yl)lactoyl-CoA (EC 2.8.3.17)
No genes
3-(indol-3-yl)acrylate + a reduced electron-transfer flavoprotein→3-(1H-indol-3-yl)propanoate + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.15)
No genes
(R)-3-(indol-3-yl)lactoyl-CoA→3-(indol-3-yl)acryloyl-CoA + H2O (EC 4.2.1.175)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information