MetaCyc Pathway: coenzyme M biosynthesis II in Pseudomonas fluorescens GW456-L13

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Reactions and Genes L-Phenylalanine (C)
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O-phospho-L-serine + H+ + sulfite→L-cysteate + phosphate (EC 2.5.1.76)
No genes
Aspartate transaminase:
L-cysteate + 2-oxoglutarate→3-sulfopyruvate + L-glutamate (EC 2.6.1.1)
PfGW456L13_2059 +0.2
PfGW456L13_2142 -0.7
PfGW456L13_2252 -0.1
PfGW456L13_2943 +0.0
PfGW456L13_2947 +0.3
PfGW456L13_3163 +0.0
PfGW456L13_3206 +0.2
PfGW456L13_3261 +0.1
PfGW456L13_3292 +0.2
PfGW456L13_3363 +0.2
PfGW456L13_4175 +0.1
PfGW456L13_4396 -1.7
PfGW456L13_4856 -0.1
PfGW456L13_4919 +0.1
PfGW456L13_4930 +0.3
PfGW456L13_733 -0.1
PfGW456L13_807 -0.1
Sulfopyruvate decarboxylase:
3-sulfopyruvate + H+→sulfoacetaldehyde + CO2 (EC 4.1.1.79)
No genes
sulfoacetaldehyde + L-cysteine→2-(sulfomethyl)thiazolidine-4-carboxylate + H+ + H2O
No genes
2-(sulfomethyl)thiazolidine-4-carboxylate + a reduced two electron carrier + H+→sulfoethylcysteine + an oxidized electron carrier
No genes
sulfoethylcysteine + H2O→coenzyme M + ammonium + pyruvate
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information