MetaCyc Pathway: chorismate biosynthesis I in Pseudomonas fluorescens GW456-L13

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Reactions and Genes L-Phenylalanine (C)
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3-deoxy-7-phosphoheptulonate synthase:
D-erythrose 4-phosphate + phosphoenolpyruvate + H2O→3-deoxy-D-arabino-heptulosonate 7-phosphate + phosphate
(EC 2.5.1.54)
PfGW456L13_2224 -0.2
PfGW456L13_2244 -1.1
PfGW456L13_2883 -0.1
3-dehydroquinate synthase:
3-deoxy-D-arabino-heptulosonate 7-phosphate→3-dehydroquinate + phosphate
(EC 4.2.3.4)
PfGW456L13_275 -4.0
3-dehydroquinate dehydratase:
3-dehydroquinate→3-dehydroshikimate + H2O
(EC 4.2.1.10)
PfGW456L13_1428 +0.3
PfGW456L13_4686 N.D.
PfGW456L13_50 -3.4
Shikimate dehydrogenase (in reverse):
3-dehydroshikimate + NADPH + H+→shikimate + NADP+
(EC 1.1.1.25)
PfGW456L13_1427 -0.0
PfGW456L13_2490 -0.2
PfGW456L13_644 -5.3
Shikimate kinase:
shikimate + ATP→shikimate 3-phosphate + ADP + H+
(EC 2.7.1.71)
PfGW456L13_276 -3.4
3-phosphoshikimate 1-carboxyvinyltransferase:
shikimate 3-phosphate + phosphoenolpyruvate→5-enolpyruvoyl-shikimate 3-phosphate + phosphate
(EC 2.5.1.19)
PfGW456L13_2178 +0.1
Chorismate synthase:
5-enolpyruvoyl-shikimate 3-phosphate→chorismate + phosphate
(EC 4.2.3.5)
PfGW456L13_4165 -2.9

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information