MetaCyc Pathway: ppGpp metabolism in Escherichia coli BW25113
| Reactions and Genes | methylglyoxal 0.008 vol% |
|---|---|
| remove | |
| Nucleoside-diphosphate kinase: GDP + ATP→GTP + ADP (EC 2.7.4.6) | |
| b0474 (adk) | N.D. |
| b2518 (ndk) | -0.7 |
| GTP diphosphokinase: GTP + ATP→pppGpp + AMP + H+ (EC 2.7.6.5) | |
| b2784 (relA) | -1.6 |
| b3650 (spoT) | +2.2 |
| Guanosine-5'-triphosphate,3'-diphosphate diphosphatase: pppGpp + H2O→ppGpp + H+ + phosphate (EC 3.6.1.40) | |
| b0049 (apaH) | -1.6 |
| b2502 (ppx) | -1.3 |
| b3779 (gpp) | +0.7 |
| Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase: pppGpp + H2O→GTP + diphosphate (EC 3.1.7.2) | |
| b3650 (spoT) | +2.2 |
| Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase: ppGpp + H2O→GDP + diphosphate (EC 3.1.7.2) | |
| b3650 (spoT) | +2.2 |
| GTP diphosphokinase: GDP + ATP→ppGpp + AMP + H+ (EC 2.7.6.5) | |
| b2784 (relA) | -1.6 |
| b3650 (spoT) | +2.2 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information