MetaCyc Pathway: myo-inositol degradation I in Pseudomonas simiae WCS417

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Reactions and Genes m-Inositol (C)
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Inositol 2-dehydrogenase:
myo-inositol + NAD+scyllo-inosose + NADH + H+
(EC 1.1.1.18)
PS417_11080 -0.0
PS417_11875 -3.4
PS417_11880 +0.4
PS417_15165 -0.0
Myo-inosose-2 dehydratase:
scyllo-inosose→3D-(3,5/4)-trihydroxycyclohexane-1,2-dione + H2O
(EC 4.2.1.44)
PS417_11855 -3.0
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione + H2O→5-deoxy-D-glucuronate + H+ (EC 3.7.1.22)
PS417_11870 -3.0
5-deoxy-D-glucuronate→5-dehydro-2-deoxy-D-gluconate (EC 5.3.1.30)
PS417_11860 -2.5
5-dehydro-2-deoxygluconokinase:
5-dehydro-2-deoxy-D-gluconate + ATP→5-dehydro-2-deoxy-D-gluconate 6-phosphate + ADP + H+
(EC 2.7.1.92)
PS417_11850 -2.7
PS417_11860 -2.5
5-dehydro-2-deoxyphosphogluconate aldolase:
5-dehydro-2-deoxy-D-gluconate 6-phosphate→glycerone phosphate + 3-oxopropanoate
(EC 4.1.2.29)
PS417_11850 -2.7
Malonate-semialdehyde dehydrogenase (acetylating):
3-oxopropanoate + coenzyme A + NAD+→acetyl-CoA + CO2 + NADH
(EC 1.2.1.18)
PS417_10925 -1.3
PS417_23725 -0.1
PS417_03250 -1.4

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information