MetaCyc Pathway: 4-hydroxybenzoate biosynthesis I (eukaryotes) in Agrobacterium fabrum C58

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Reactions and Genes D-Saccharic potassium salt (C)
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Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
Atu0235 +0.0
Atu0529 -0.0
Atu1011 -0.3
Atu1589 -2.5
Atu1848 -2.6
Atu2015 -1.8
Atu2196 N.D.
Atu3612 N.D.
Atu4266 +0.2
Atu4278 -0.3
Indolelactate dehydrogenase (in reverse):
3-(4-hydroxyphenyl)pyruvate + NADH + H+→(R)-3-(4-hydroxyphenyl)lactate + NAD+
(EC 1.1.1.110)
No genes
Cinnamoyl-CoA:phenyllactate CoA-transferase:
(R)-3-(4-hydroxyphenyl)lactate + (E)-4-coumaroyl-CoA→4-coumarate + (R)-3-(4-hydroxyphenyl)lactoyl-CoA
(EC 2.8.3.17)
No genes
4-coumarate + H2O→4-hydroxybenzaldehyde + acetate
No genes
4-hydroxybenzaldehyde dehydrogenase:
4-hydroxybenzaldehyde + NAD+ + H2O→4-hydroxybenzoate + NADH + 2 H+
(EC 1.2.1.64)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information