MetaCyc Pathway: L-tyrosine degradation I in Pseudomonas simiae WCS417

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Reactions and Genes D-Glucose-6-Phosphate (C)
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Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
PS417_08130 -0.5
PS417_08560 +0.2
PS417_09070 +0.2
PS417_09120 +0.1
PS417_11840 -0.0
PS417_12775 -0.1
PS417_12985 -0.0
PS417_13545 +0.1
PS417_14865 +0.0
PS417_15040 +0.1
PS417_15990 -0.1
PS417_18690 +0.5
PS417_19025 +0.0
PS417_19385 -0.0
PS417_19910 +0.1
PS417_21030 -1.7
PS417_21275 -0.1
PS417_23120 +0.1
PS417_23365 +0.0
PS417_27730 +0.0
PS417_28165 -0.2
PS417_04425 -0.5
4-hydroxyphenylpyruvate dioxygenase:
3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2 (EC 1.13.11.27)
PS417_14005 -0.2
PS417_24445 +0.1
Homogentisate 1,2-dioxygenase:
homogentisate + dioxygen→4-maleyl-acetoacetate + H+ (EC 1.13.11.5)
PS417_05015 +0.2
Maleylacetoacetate isomerase:
4-maleyl-acetoacetate→4-fumaryl-acetoacetate (EC 5.2.1.2)
PS417_05025 -0.2
Fumarylacetoacetase:
4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+ (EC 3.7.1.2)
PS417_05020 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information