MetaCyc Pathway: L-tyrosine degradation V (reductive Stickland reaction) in Pseudomonas simiae WCS417

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Reactions and Genes D-Glucose-6-Phosphate (C)
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Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
PS417_08130 -0.5
PS417_08560 +0.2
PS417_09070 +0.2
PS417_09120 +0.1
PS417_11840 -0.0
PS417_12775 -0.1
PS417_12985 -0.0
PS417_13545 +0.1
PS417_14865 +0.0
PS417_15040 +0.1
PS417_15990 -0.1
PS417_18690 +0.5
PS417_19025 +0.0
PS417_19385 -0.0
PS417_19910 +0.1
PS417_21030 -1.7
PS417_21275 -0.1
PS417_23120 +0.1
PS417_23365 +0.0
PS417_27730 +0.0
PS417_28165 -0.2
PS417_04425 -0.5
Indolelactate dehydrogenase (in reverse):
3-(4-hydroxyphenyl)pyruvate + NADH + H+→(R)-3-(4-hydroxyphenyl)lactate + NAD+
(EC 1.1.1.110)
No genes
Cinnamoyl-CoA:phenyllactate CoA-transferase:
(R)-3-(4-hydroxyphenyl)lactate + (E)-4-coumaroyl-CoA→4-coumarate + (R)-3-(4-hydroxyphenyl)lactoyl-CoA
(EC 2.8.3.17)
No genes
4-coumarate + a reduced electron-transfer flavoprotein→phloretate + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.15)
No genes
(R)-3-(4-hydroxyphenyl)lactoyl-CoA→(E)-4-coumaroyl-CoA + H2O (EC 4.2.1.175)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information