MetaCyc Pathway: adenosine nucleotides degradation II in Escherichia coli BW25113

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Reactions and Genes Aluminum chloride 5 mM
remove
5'-nucleotidase:
AMP + H2O→adenosine + phosphate
(EC 3.1.3.5)
b0383 (phoA) -0.1
b0480 (ushA) +0.1
b2291 (yfbR) +0.1
b2744 (surE) -0.2
b4055 (aphA) -1.2
b4374 (yjjG) +0.0
Adenosine deaminase:
adenosine + H+ + H2O→inosine + ammonium
(EC 3.5.4.4)
b1623 (add) -0.1
b2593 (yfiH) -1.9
Purine-nucleoside phosphorylase:
inosine + phosphate→hypoxanthine + α-D-ribose-1-phosphate
(EC 2.4.2.1)
b0391 (yaiE) +0.0
b2407 (xapA) -0.3
b2593 (yfiH) -1.9
b4384 (deoD) -0.4
Xanthine dehydrogenase:
hypoxanthine + NAD+ + H2O→xanthine + NADH + H+
(EC 1.17.1.4)
b0284 (yagR) +0.2
b0285 (yagS) +0.4
b2866 (xdhA) -0.0
b2867 (xdhB) +0.6
b2868 (xdhC) +0.3
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+
(EC 1.17.1.4)
b0284 (yagR) +0.2
b0285 (yagS) +0.4
b2866 (xdhA) -0.0
b2867 (xdhB) +0.6
b2868 (xdhC) +0.3

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information