MetaCyc Pathway: 4-deoxy-L-threo-hex-4-enopyranuronate degradation in Agrobacterium fabrum C58

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Reactions and Genes D-Galacturonic Acid (C)
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4-deoxy-L-threo-hex-4-enopyranuronate→5-dehydro-4-deoxy-D-glucuronate (EC 4.2.99.25)
Atu3145 -0.3
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase:
5-dehydro-4-deoxy-D-glucuronate→3-deoxy-D-glycero-2,5-hexodiulosonate
(EC 5.3.1.17)
Atu3142 -1.8
2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase (in reverse):
3-deoxy-D-glycero-2,5-hexodiulosonate + NADH + H+→2-dehydro-3-deoxy-D-gluconate + NAD+
(EC 1.1.1.127)
Atu3531 +0.3
2-dehydro-3-deoxy-D-gluconate + ATP→2-dehydro-3-deoxy-D-gluconate 6-phosphate + ADP + H+ (EC 2.7.1.178; 2.7.1.45)
Atu2296 +0.1
2-dehydro-3-deoxy-phosphogluconate aldolase:
2-dehydro-3-deoxy-D-gluconate 6-phosphate→D-glyceraldehyde 3-phosphate + pyruvate
(EC 4.1.2.14; 4.1.2.55)
Atu4494 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information