MetaCyc Pathway: ureide biosynthesis in Pseudomonas sp. RS175

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Reactions and Genes Adenosine (C) 10 mM
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IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+
(EC 1.1.1.205)
PFR28_00310 N.D.
PFR28_01298 +0.0
PFR28_01858 +0.3
5'-nucleotidase:
XMP + H2O→xanthosine + phosphate
(EC 3.1.3.5)
PFR28_00424 -1.2
PFR28_00964 +0.2
Purine-nucleoside phosphorylase:
xanthosine + phosphate→xanthine + α-D-ribose-1-phosphate
(EC 2.4.2.1)
PFR28_04284 +0.0
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+
(EC 1.17.1.4)
PFR28_01063 -1.4
PFR28_01064 -1.5
PFR28_03803 +0.1
PFR28_03804 +0.1
Urate oxidase:
urate + dioxygen + H2O→(S)-5-hydroxyisourate + hydrogen peroxide
(EC 1.7.3.3)
PFR28_02168 +0.0
PFR28_03143 -4.0
PFR28_03553 +0.1
Hydroxyisourate hydrolase:
(S)-5-hydroxyisourate + H2O→(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+
(EC 3.5.2.17)
PFR28_03142 -3.9
(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+→(S)-(+)-allantoin + CO2 (EC 4.1.1.97)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information