MetaCyc Pathway: superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis in Escherichia coli BW25113

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Reactions and Genes Chloride 750 mM
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Phosphoglucomutase (in reverse):
D-glucopyranose 6-phosphate→α-D-glucopyranose 1-phosphate (EC 5.4.2.2)
b0688 (pgm) +0.0
b3176 (glmM) N.D.
UTP-monosaccharide-1-phosphate uridylyltransferase:
α-D-glucopyranose 1-phosphate + H+ + UTP→UDP-α-D-glucose + diphosphate (EC 2.7.7.64; 2.7.7.9)
b1236 (galU) +0.4
b2042 (galF) -0.1
UDP-glucose 4-epimerase:
UDP-α-D-glucose→UDP-α-D-galactose (EC 5.1.3.2)
b0759 (galE) -1.8
UDP-glucose 6-dehydrogenase:
UDP-α-D-glucose + 2 NAD+ + H2O→UDP-α-D-glucuronate + 2 NADH + 3 H+ (EC 1.1.1.22)
b2028 (ugd) -2.6
b3787 (rffD) -1.2
UDP-galactopyranose mutase:
UDP-α-D-galactose→UDP-α-D-galactofuranose (EC 5.4.99.9)
b2036 (glf) -0.1
UDP-glucuronate 4-epimerase:
UDP-α-D-glucuronate→UDP-α-D-galacturonate (EC 5.1.3.6)
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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information