MetaCyc Pathway: Entner-Doudoroff pathway III (semi-phosphorylative) in Agrobacterium fabrum C58

Reactions and Genes	gluconate (C)
Glucose 1-dehydrogenase (NADP(+)): D-glucopyranose + NADP+→D-glucono-1,5-lactone + NADPH + H+ (EC 1.1.1.119; 1.1.1.360)
No genes
Gluconolactonase: D-glucono-1,5-lactone + H2O→D-gluconate + H+ (spontaneous) (EC 3.1.1.17)
Atu4029	-0.1
D-gluconate→2-dehydro-3-deoxy-D-gluconate + H2O (EC 4.2.1.140; 4.2.1.39)
Atu0270	+0.2
Atu1406	+0.1
Atu4196	+0.2
Atu5458	-0.0
2-dehydro-3-deoxy-D-gluconate + ATP→2-dehydro-3-deoxy-D-gluconate 6-phosphate + ADP + H+ (EC 2.7.1.178; 2.7.1.45)
Atu2296	+3.2
2-dehydro-3-deoxy-phosphogluconate aldolase: 2-dehydro-3-deoxy-D-gluconate 6-phosphate→D-glyceraldehyde 3-phosphate + pyruvate (EC 4.1.2.14; 4.1.2.55)
Atu4494	N.D.
D-glyceraldehyde 3-phosphate + NAD(P)+ + H2O→3-phospho-D-glycerate + NAD(P)H + 2 H+ (EC 1.2.1.90)
No genes
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
Atu3016	+0.5
Atu3017	-0.2
Atu3469	-1.0
Phosphopyruvate hydratase: 2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
Atu1426	N.D.
Pyruvate kinase (in reverse): phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
Atu3762	N.D.

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information