MetaCyc Pathway: L-tyrosine degradation I in Agrobacterium fabrum C58

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Reactions and Genes D-Quinic (C)
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Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
Atu0235 +0.0
Atu0529 -0.1
Atu1011 +0.1
Atu1589 -4.1
Atu1848 -0.1
Atu2015 -4.2
Atu2196 N.D.
Atu3612 N.D.
Atu4266 -0.2
Atu4278 -0.1
4-hydroxyphenylpyruvate dioxygenase:
3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2 (EC 1.13.11.27)
Atu4529 -6.8
Homogentisate 1,2-dioxygenase:
homogentisate + dioxygen→4-maleyl-acetoacetate + H+ (EC 1.13.11.5)
No genes
Maleylacetoacetate isomerase:
4-maleyl-acetoacetate→4-fumaryl-acetoacetate (EC 5.2.1.2)
Atu0836 +0.0
Fumarylacetoacetase:
4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+ (EC 3.7.1.2)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information