MetaCyc Pathway: ketolysis in Pseudomonas putida KT2440

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Reactions and Genes rac-3-Hydroxypentanoic Acid (C)
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3-hydroxybutyrate dehydrogenase:
(R)-3-hydroxybutanoate + NAD+→acetoacetate + NADH + H+
(EC 1.1.1.30)
PP_2784 +0.3
PP_3073 -0.8
3-oxoacid CoA-transferase:
acetoacetate + succinyl-CoA→acetoacetyl-CoA + succinate
(EC 2.8.3.5)
PP_3122 -3.5
PP_3123 -4.9
Acetyl-CoA C-acyltransferase (in reverse):
acetoacetyl-CoA + coenzyme A→2 acetyl-CoA
(EC 2.3.1.16; 2.3.1.9)
PP_0582 +0.0
PP_1377 +0.2
PP_2051 -0.0
PP_2137 -0.1
PP_2215 +0.1
PP_3280 -0.5
PP_3355 -0.1
PP_3754 +0.0
PP_4636 +0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information