MetaCyc Pathway: histamine degradation in Pseudomonas putida KT2440

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Reactions and Genes Valerolactone (C)
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Diamine oxidase:
histamine + dioxygen + H2O→imidazole acetaldehyde + ammonium + hydrogen peroxide
(EC 1.4.3.22)
No genes
Histamine N-methyltransferase:
histamine + S-adenosyl-L-methionineNτ-methylhistamine + S-adenosyl-L-homocysteine + H+
(EC 2.1.1.8)
No genes
Aldehyde dehydrogenase (NAD(+)):
imidazole acetaldehyde + NAD+ + H2O→4-imidazoleacetate + NADH + 2 H+
(EC 1.2.1.3)
PP_0545 -0.1
PP_0665 +0.0
PP_0708 -0.0
PP_1948 +0.3
PP_2487 +0.0
PP_2589 -0.2
PP_2680 +1.3
PP_2694 +0.6
PP_3270 +0.3
PP_3463 -0.1
PP_3646 -0.1
PP_5258 +0.1
PP_5278 -0.9
PP_5372 +0.4

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information