MetaCyc Pathway: propanoyl-CoA degradation II in Pseudomonas putida KT2440

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Reactions and Genes DL-3-Aminoisobutyric (N)
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Acyl-CoA oxidase:
propanoyl-CoA + dioxygen→acryloyl-CoA + hydrogen peroxide
(EC 1.3.3.6)
No genes
acryloyl-CoA + H2O→3-hydroxypropanoyl-CoA (EC 4.2.1.116)
PP_2217 -1.2
3-hydroxyisobutyryl-CoA hydrolase:
3-hydroxypropanoyl-CoA + H2O→3-hydroxypropanoate + coenzyme A + H+
(EC 3.1.2.4)
PP_3491 +0.1
3-hydroxypropionate dehydrogenase:
3-hydroxypropanoate + NAD+→3-oxopropanoate + NADH + H+
(EC 1.1.1.59)
No genes
Malonate-semialdehyde dehydrogenase (acetylating):
3-oxopropanoate + coenzyme A + NAD+→acetyl-CoA + CO2 + NADH
(EC 1.2.1.18)
PP_0597 -1.7
PP_4667 -0.4

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information