MetaCyc Pathway: ureide biosynthesis in Pseudomonas putida KT2440

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Reactions and Genes Adenine (N)
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IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)
PP_1031 N.D.
5'-nucleotidase:
XMP + H2O→xanthosine + phosphate (EC 3.1.3.5)
PP_1414 +0.1
PP_1620 +0.1
PP_2531 -0.1
Purine-nucleoside phosphorylase:
xanthosine + phosphate→xanthine + α-D-ribose-1-phosphate (EC 2.4.2.1)
PP_5158 +0.1
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)
PP_3309 +0.0
PP_3310 -0.1
PP_4278 -0.3
PP_4279 -0.3
Urate oxidase:
urate + dioxygen + H2O→(S)-5-hydroxyisourate + hydrogen peroxide (EC 1.7.3.3)
PP_1290 -0.0
PP_4286 -1.4
Hydroxyisourate hydrolase:
(S)-5-hydroxyisourate + H2O→(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+ (EC 3.5.2.17)
PP_4285 -0.9
(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+→(S)-(+)-allantoin + CO2 (EC 4.1.1.97)
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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information