MetaCyc Pathway: dopamine degradation in Pseudomonas putida KT2440

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Reactions and Genes 1,6-Hexanediamine (N)
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Monoamine oxidase:
dopamine + dioxygen + H2O→3,4-dihydroxyphenylacetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
PP_4983 +0.2
Catechol O-methyltransferase:
dopamine + S-adenosyl-L-methionine→3-methoxytyramine + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.6)
No genes
Aryl sulfotransferase:
dopamine + 3'-phosphoadenylyl-sulfate→dopamine 3-O-sulfate + adenosine 3',5'-bisphosphate + H+ (EC 2.8.2.1)
No genes
Aldehyde dehydrogenase (NAD(+)):
3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O→(3,4-dihydroxyphenyl)acetate + NADH + 2 H+ (EC 1.2.1.3)
PP_0545 +0.0
PP_0665 -0.0
PP_0708 -0.1
PP_1948 +0.1
PP_2487 +0.0
PP_2589 -0.3
PP_2680 +0.1
PP_2694 +0.0
PP_3270 +0.1
PP_3463 +0.0
PP_3646 -0.0
PP_5258 -0.0
PP_5278 -1.6
PP_5372 +0.0
Catechol O-methyltransferase:
(3,4-dihydroxyphenyl)acetate + S-adenosyl-L-methionine→homovanillate + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.6)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information