MetaCyc Pathway: aromatic biogenic amine degradation (bacteria) in Pseudomonas putida KT2440

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Reactions and Genes D-Lysine (N)
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Octopamine dehydratase:
octopamine→(4-hydroxyphenyl)acetaldehyde + ammonium (EC 4.2.1.87)
No genes
tyramine + an oxidized electron carrier + H2O→(4-hydroxyphenyl)acetaldehyde + ammonium + a reduced two electron carrier
No genes
Monoamine oxidase:
tyramine + dioxygen + H2O→(4-hydroxyphenyl)acetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
PP_4983 +0.1
Monoamine oxidase:
dopamine + dioxygen + H2O→3,4-dihydroxyphenylacetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
PP_4983 +0.1
Synephrine dehydratase:
(R)-synephrine→(4-hydroxyphenyl)acetaldehyde + methylamine (EC 4.2.1.88)
No genes
4-hydroxyphenylacetaldehyde dehydrogenase:
(4-hydroxyphenyl)acetaldehyde + NAD+ + H2O→(4-hydroxyphenyl)acetate + NADH + 2 H+ (EC 1.2.1.53)
No genes
Aldehyde dehydrogenase (NAD(+)):
3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O→(3,4-dihydroxyphenyl)acetate + NADH + 2 H+ (EC 1.2.1.3)
PP_0545 -0.0
PP_0665 +0.1
PP_0708 +0.1
PP_1948 -0.0
PP_2487 -0.0
PP_2589 -0.1
PP_2680 -0.1
PP_2694 +0.1
PP_3270 -0.2
PP_3463 +0.1
PP_3646 -0.1
PP_5258 -2.0
PP_5278 -0.0
PP_5372 -0.0
(4-hydroxyphenyl)acetate + FADH2 + dioxygen→(3,4-dihydroxyphenyl)acetate + FAD + H+ + H2O (EC 1.14.14.9)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information