MetaCyc Pathway: L-tryptophan degradation X (mammalian, via tryptamine) in Pseudomonas putida KT2440

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Reactions and Genes D-Lysine (N)
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L-tryptophan + H+→tryptamine + CO2 (EC 4.1.1.105; 4.1.1.28)
PP_2552 -0.2
Monoamine oxidase:
tryptamine + dioxygen + H2O→(indol-3-yl)acetaldehyde + ammonium + hydrogen peroxide
(EC 1.4.3.4)
PP_4983 +0.1
Indole-3-acetaldehyde reductase (NADPH) (in reverse):
(indol-3-yl)acetaldehyde + NADPH + H+→(indol-3-yl)ethanol + NADP+
(EC 1.1.1.191; 1.1.1.2)
No genes
Aldehyde dehydrogenase (NAD(+)):
(indol-3-yl)acetaldehyde + NAD+ + H2O→(indol-3-yl)acetate + NADH + 2 H+
(EC 1.2.1.3)
PP_0545 -0.0
PP_0665 +0.1
PP_0708 +0.1
PP_1948 -0.0
PP_2487 -0.0
PP_2589 -0.1
PP_2680 -0.1
PP_2694 +0.1
PP_3270 -0.2
PP_3463 +0.1
PP_3646 -0.1
PP_5258 -2.0
PP_5278 -0.0
PP_5372 -0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information