MetaCyc Pathway: thymine degradation in Pseudomonas putida KT2440

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Reactions and Genes 3-aminobutyric (N)
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Dihydropyrimidine dehydrogenase (NADP(+)) (in reverse):
thymine + NADPH + H+→5,6-dihydrothymine + NADP+ (EC 1.3.1.2)
PP_4038 -1.7
Dihydropyrimidinase:
5,6-dihydrothymine + H2O→3-(carbamoylamino)-2-methylpropanoate + H+ (EC 3.5.2.2)
PP_4036 -1.8
Beta-ureidopropionase:
3-(carbamoylamino)-2-methylpropanoate + 2 H+ + H2O→(R)-3-amino-2-methylpropanoate + ammonium + CO2 (EC 3.5.1.6)
PP_0614 -0.0
PP_4034 -0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information