MetaCyc Pathway: polyhydroxybutanoate biosynthesis in Brevundimonas sp. GW460-12-10-14-LB2

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Reactions and Genes D-Glucose (C); 30C
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Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)
A4249_RS10470 -0.0
A4249_RS11165 +0.1
A4249_RS12605 +0.2
A4249_RS14640 +0.7
Acetoacetyl-CoA reductase (in reverse):
acetoacetyl-CoA + NADPH + H+→(3R)-3-hydroxybutanoyl-CoA + NADP+ (EC 1.1.1.36)
A4249_RS00310 +1.6
(3R)-3-hydroxybutanoyl-CoA + poly-[(R)-3-hydroxybutanoate]→poly-[(R)-3-hydroxybutanoate] + coenzyme A (EC 2.3.1.304)
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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information