| Reactions and Genes | L-Leucine (C) |
|---|
| remove |
| a 2,3,4-saturated fatty acid + ATP + coenzyme A→a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate |
| No genes |
Acyl-CoA oxidase:
a 2,3,4-saturated fatty acyl CoA + dioxygen→a (2E)-2-enoyl-CoA + hydrogen peroxide (EC 1.3.3.6) |
| No genes |
Enoyl-CoA hydratase (in reverse):
a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA (EC 4.2.1.17) |
| QEN71_RS01230 | +0.1 |
| QEN71_RS02065 | +0.0 |
| QEN71_RS02075 | -0.2 |
| QEN71_RS04150 | -0.1 |
| QEN71_RS05365 | -0.0 |
| QEN71_RS06625 | -0.2 |
| QEN71_RS08225 | N.D. |
| QEN71_RS10900 | -0.0 |
| QEN71_RS12380 | -1.1 |
| QEN71_RS12385 | -0.6 |
| QEN71_RS15965 | +0.1 |
| QEN71_RS16060 | +0.2 |
| QEN71_RS19420 | -1.4 |
| QEN71_RS19500 | -0.2 |
| QEN71_RS21890 | +0.2 |
| QEN71_RS22700 | +0.2 |
| QEN71_RS24020 | +0.2 |
| QEN71_RS24025 | -0.1 |
| QEN71_RS26140 | -0.3 |
| QEN71_RS27495 | +0.2 |
| QEN71_RS27510 | +0.2 |
| QEN71_RS29945 | +0.0 |
| QEN71_RS30540 | +0.7 |
| QEN71_RS30550 | N.D. |
| QEN71_RS30645 | +0.4 |
| QEN71_RS32940 | -0.2 |
| QEN71_RS33220 | -0.1 |
| QEN71_RS35840 | -0.1 |
| QEN71_RS38515 | N.D. |
| QEN71_RS39250 | -0.1 |
| QEN71_RS39410 | -0.1 |
| QEN71_RS39560 | +0.2 |
3-hydroxyacyl-CoA dehydrogenase:
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+→a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+ (EC 1.1.1.35) |
| QEN71_RS02065 | +0.0 |
| QEN71_RS21890 | +0.2 |
| QEN71_RS24020 | +0.2 |
| QEN71_RS29945 | +0.0 |
| QEN71_RS37855 | N.D. |
Acetyl-CoA C-acyltransferase (in reverse):
a 2,3,4-saturated 3-oxoacyl-CoA + coenzyme A→a 2,3,4-saturated fatty acyl CoA + acetyl-CoA (EC 2.3.1.16) |
| QEN71_RS01125 | +0.1 |
| QEN71_RS02070 | -0.1 |
| QEN71_RS14170 | +0.1 |
| QEN71_RS15980 | -0.1 |
| QEN71_RS18320 | -1.1 |
| QEN71_RS18730 | +0.0 |
| QEN71_RS21880 | +0.1 |
| QEN71_RS22175 | +0.0 |
| QEN71_RS22200 | -1.3 |
| QEN71_RS22970 | -0.1 |
| QEN71_RS27505 | -0.0 |
Citrate (Si)-synthase:
acetyl-CoA + oxaloacetate + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16; 2.3.3.3) |
| QEN71_RS02900 | +0.4 |
| QEN71_RS11110 | -0.0 |
| QEN71_RS17600 | -3.3 |
| QEN71_RS38525 | +0.2 |
| QEN71_RS39030 | +0.2 |
Aconitate hydratase:
citrate→cis-aconitate + H2O (EC 4.2.1.3) |
| QEN71_RS17535 | +0.2 |
| QEN71_RS19735 | -0.2 |
| QEN71_RS31060 | -0.5 |
| QEN71_RS41385 | +0.0 |
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3) |
| QEN71_RS17535 | +0.2 |
| QEN71_RS19735 | -0.2 |
| QEN71_RS31060 | -0.5 |
| QEN71_RS41385 | +0.0 |
Isocitrate lyase:
D-threo-isocitrate→glyoxylate + succinate (EC 4.1.3.1) |
| QEN71_RS06270 | -3.3 |
Malate synthase:
acetyl-CoA + glyoxylate + H2O→(S)-malate + coenzyme A + H+ (EC 2.3.3.9) |
| QEN71_RS06250 | +0.2 |
| QEN71_RS31820 | -0.6 |
Succinate dehydrogenase (ubiquinone):
succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol (EC 1.3.5.1) |
| QEN71_RS17585 | N.D. |
| QEN71_RS17590 | N.D. |
| QEN71_RS38665 | N.D. |
| QEN71_RS38670 | N.D. |
Fumarate hydratase (in reverse):
fumarate + H2O→(S)-malate (EC 4.2.1.2) |
| QEN71_RS04360 | -0.2 |
| QEN71_RS11740 | -0.1 |
| QEN71_RS23780 | +0.1 |
Malate dehydrogenase:
(S)-malate + NAD+→oxaloacetate + NADH + H+ (EC 1.1.1.37; 1.1.1.38) |
| QEN71_RS10905 | +0.2 |
| QEN71_RS17565 | N.D. |
| QEN71_RS36375 | +0.3 |
Phosphoenolpyruvate carboxykinase (ATP):
oxaloacetate + ATP→phosphoenolpyruvate + ADP + CO2 (EC 4.1.1.49) |
| No genes |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information