MetaCyc Pathway: fatty acid β-oxidation I (generic) in Paraburkholderia sabiae LMG 24235

Add experiment(s):


Reactions and Genes L-Leucine (C)
remove
a 2,3,4-saturated fatty acid + ATP + coenzyme A→a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate
No genes
Dodecenoyl-CoA isomerase:
a (3Z)-3-enoyl-CoA→a (2E)-2-enoyl-CoA
(EC 5.3.3.8)
QEN71_RS02065 +0.0
QEN71_RS21890 +0.2
QEN71_RS29945 +0.0
3-hydroxybutyryl-CoA epimerase:
a 2,3,4-saturated (3R)-3-hydroxyacyl-CoA→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA
(EC 5.1.2.3)
QEN71_RS21890 +0.2
QEN71_RS29945 +0.0
a 2,3,4-saturated fatty acyl CoA + an oxidized electron-transfer flavoprotein + H+→a (2E)-2-enoyl-CoA + a reduced electron-transfer flavoprotein
No genes
Enoyl-CoA hydratase (in reverse):
a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA
(EC 4.2.1.17)
QEN71_RS01230 +0.1
QEN71_RS02065 +0.0
QEN71_RS02075 -0.2
QEN71_RS04150 -0.1
QEN71_RS05365 -0.0
QEN71_RS06625 -0.2
QEN71_RS08225 N.D.
QEN71_RS10900 -0.0
QEN71_RS12380 -1.1
QEN71_RS12385 -0.6
QEN71_RS15965 +0.1
QEN71_RS16060 +0.2
QEN71_RS19420 -1.4
QEN71_RS19500 -0.2
QEN71_RS21890 +0.2
QEN71_RS22700 +0.2
QEN71_RS24020 +0.2
QEN71_RS24025 -0.1
QEN71_RS26140 -0.3
QEN71_RS27495 +0.2
QEN71_RS27510 +0.2
QEN71_RS29945 +0.0
QEN71_RS30540 +0.7
QEN71_RS30550 N.D.
QEN71_RS30645 +0.4
QEN71_RS32940 -0.2
QEN71_RS33220 -0.1
QEN71_RS35840 -0.1
QEN71_RS38515 N.D.
QEN71_RS39250 -0.1
QEN71_RS39410 -0.1
QEN71_RS39560 +0.2
3-hydroxyacyl-CoA dehydrogenase:
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+→a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+
(EC 1.1.1.35)
QEN71_RS02065 +0.0
QEN71_RS21890 +0.2
QEN71_RS24020 +0.2
QEN71_RS29945 +0.0
QEN71_RS37855 N.D.
Acetyl-CoA C-acyltransferase (in reverse):
a 2,3,4-saturated 3-oxoacyl-CoA + coenzyme A→a 2,3,4-saturated fatty acyl CoA + acetyl-CoA
(EC 2.3.1.16)
QEN71_RS01125 +0.1
QEN71_RS02070 -0.1
QEN71_RS14170 +0.1
QEN71_RS15980 -0.1
QEN71_RS18320 -1.1
QEN71_RS18730 +0.0
QEN71_RS21880 +0.1
QEN71_RS22175 +0.0
QEN71_RS22200 -1.3
QEN71_RS22970 -0.1
QEN71_RS27505 -0.0

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information