MetaCyc Pathway: Entner-Doudoroff pathway II (non-phosphorylative) in Paraburkholderia sabiae LMG 24235

Reactions and Genes	D-Sorbitol (C)
Glucose 1-dehydrogenase (NADP(+)): D-glucopyranose + NADP+→D-glucono-1,5-lactone + NADPH + H+ (EC 1.1.1.119; 1.1.1.360)
No genes
Gluconolactonase: D-glucono-1,5-lactone + H2O→D-gluconate + H+ (spontaneous) (EC 3.1.1.17)
QEN71_RS13590	-0.1
QEN71_RS18015	-0.1
QEN71_RS18960	+0.1
QEN71_RS38785	+0.1
D-gluconate→2-dehydro-3-deoxy-D-gluconate + H2O (EC 4.2.1.140; 4.2.1.39)
QEN71_RS02295	-0.1
QEN71_RS14610	-0.1
QEN71_RS30680	+0.2
QEN71_RS39295	-0.2
2-dehydro-3-deoxy-D-gluconate→D-glyceraldehyde + pyruvate (EC 4.1.2.51)
No genes
D-glyceraldehyde + an oxidized electron carrier + H2O→D-glycerate + a reduced two electron carrier + H+ (EC 1.2.99.8)
QEN71_RS00050	+0.1
QEN71_RS07095	+0.1
QEN71_RS11040	-0.1
QEN71_RS11670	-0.1
QEN71_RS13660	+0.1
QEN71_RS16945	+0.3
QEN71_RS19510	+0.1
QEN71_RS20195	+0.7
QEN71_RS20440	+0.2
QEN71_RS21070	+0.1
QEN71_RS23580	+0.2
QEN71_RS24925	+0.1
QEN71_RS31880	+0.4
QEN71_RS31965	+0.0
QEN71_RS32565	+0.5
QEN71_RS34295	-0.4
QEN71_RS35780	-0.0
QEN71_RS37085	+0.2
QEN71_RS38180	+0.2
QEN71_RS38780	+0.0
QEN71_RS39635	+0.6
QEN71_RS41285	-0.1
QEN71_RS42030	+0.0
D-glycerate + ATP→2-phospho-D-glycerate + ADP + H+ (EC 2.7.1.165)
QEN71_RS12190	+0.3
Phosphopyruvate hydratase: 2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
QEN71_RS05880	N.D.
QEN71_RS41510	+0.2
Pyruvate kinase (in reverse): phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
QEN71_RS02430	-1.3
QEN71_RS12195	-0.1
QEN71_RS41440	-0.2
Pyruvate synthase: pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster→acetyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster (EC 1.2.7.1)
No genes

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information