MetaCyc Pathway: superpathway of L-arginine, putrescine, and 4-aminobutanoate degradation in Paraburkholderia sabiae LMG 24235

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Reactions and Genes 2-Deoxy-D-Ribose (C)
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Arginine decarboxylase:
L-arginine + H+→agmatine + CO2 (EC 4.1.1.19)
QEN71_RS25000 N.D.
Agmatinase:
agmatine + H2O→putrescine + urea (EC 3.5.3.11)
QEN71_RS03400 +0.1
QEN71_RS05095 N.D.
QEN71_RS11320 -0.1
Putrescine aminotransferase:
putrescine + 2-oxoglutarate→4-aminobutanal + L-glutamate (EC 2.6.1.82)
No genes
Glutamate--putrescine ligase:
putrescine + ATP + L-glutamate→γ-glutamyl-L-putrescine + ADP + H+ + phosphate (EC 6.3.1.11)
QEN71_RS12935 -2.6
Aminobutyraldehyde dehydrogenase:
4-aminobutanal + NAD+ + H2O→4-aminobutanoate + NADH + 2 H+ (EC 1.2.1.19)
QEN71_RS00050 +0.0
QEN71_RS00575 -0.5
QEN71_RS07095 +0.2
QEN71_RS11040 -0.0
QEN71_RS11670 -0.4
QEN71_RS13660 +0.1
QEN71_RS16945 +0.0
QEN71_RS19510 -0.1
QEN71_RS20195 -2.9
QEN71_RS20440 -0.1
QEN71_RS21070 +0.0
QEN71_RS23580 +0.3
QEN71_RS24925 +0.1
QEN71_RS31880 +0.1
QEN71_RS31965 +0.4
QEN71_RS32565 +0.0
QEN71_RS34295 +0.6
QEN71_RS35780 -0.0
QEN71_RS37085 -0.5
QEN71_RS38180 +0.3
QEN71_RS38780 +0.2
QEN71_RS39635 +0.1
QEN71_RS41285 +0.0
QEN71_RS42030 -0.0
γ-glutamyl-L-putrescine + dioxygen + H2O→4-(γ-L-glutamylamino)butanal + ammonium + hydrogen peroxide (EC 1.4.3.M3)
No genes
4-(γ-L-glutamylamino)butanal + NAD(P)+ + H2O→4-(γ-L-glutamylamino)butanoate + NAD(P)H + 2 H+ (EC 1.2.1.99)
No genes
Gamma-glutamyl-gamma-aminobutyrate hydrolase:
4-(γ-L-glutamylamino)butanoate + H2O→4-aminobutanoate + L-glutamate (EC 3.5.1.94)
QEN71_RS09510 +0.2
QEN71_RS12930 +1.3
QEN71_RS42520 -0.5
4-aminobutyrate transaminase:
4-aminobutanoate + 2-oxoglutarate→succinate semialdehyde + L-glutamate (EC 2.6.1.19)
QEN71_RS14680 -0.0
QEN71_RS19980 -0.1
QEN71_RS21530 -1.5
Succinate-semialdehyde dehydrogenase:
succinate semialdehyde + NAD+ + H2O→succinate + NADH + 2 H+ (EC 1.2.1.24)
No genes
succinate semialdehyde + NADP+ + H2O→succinate + NADPH + 2 H+ (EC 1.2.1.79)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information