MetaCyc Pathway: palmitate biosynthesis II (type II fatty acid synthase) in Paraburkholderia sabiae LMG 24235

Add experiment(s):


Reactions and Genes L-Rhamnose (C)
remove
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
an acetoacetyl-[acp] + NADPH + H+→a (3R)-3-hydroxybutanoyl-[acp] + NADP+ (EC 1.1.1.100)
QEN71_RS01840 -0.1
QEN71_RS02665 -0.1
QEN71_RS02810 +0.1
QEN71_RS03865 +0.8
QEN71_RS04555 N.D.
QEN71_RS07495 -0.4
QEN71_RS08210 -0.3
QEN71_RS08280 +0.6
QEN71_RS10120 +0.4
QEN71_RS11605 +0.1
QEN71_RS12650 -2.5
QEN71_RS12790 +0.1
QEN71_RS13180 +0.2
QEN71_RS15615 +0.0
QEN71_RS15890 +0.2
QEN71_RS15970 N.D.
QEN71_RS16910 -0.5
QEN71_RS16930 N.D.
QEN71_RS18940 +0.1
QEN71_RS19320 +0.2
QEN71_RS19875 +0.2
QEN71_RS22470 +0.1
QEN71_RS22960 -0.0
QEN71_RS24385 N.D.
QEN71_RS24930 +0.1
QEN71_RS25895 +0.2
QEN71_RS27100 +0.2
QEN71_RS29765 +0.4
QEN71_RS30005 -0.5
QEN71_RS30200 +0.3
QEN71_RS30445 +0.0
QEN71_RS31020 +0.2
QEN71_RS31395 +0.2
QEN71_RS32355 +0.1
QEN71_RS32915 +0.0
QEN71_RS33390 -0.1
QEN71_RS33420 +0.0
QEN71_RS33735 +0.1
QEN71_RS33860 N.D.
QEN71_RS34325 +0.4
QEN71_RS34445 -0.7
QEN71_RS35630 -0.1
QEN71_RS36135 N.D.
QEN71_RS36540 -0.1
QEN71_RS36910 -0.2
QEN71_RS37725 -0.0
QEN71_RS38560 -0.1
QEN71_RS38920 -0.1
QEN71_RS39090 +0.4
QEN71_RS39175 -0.4
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxybutanoyl-[acp]→a (2E)-but-2-enoyl-[acp] + H2O (EC 4.2.1.59)
QEN71_RS06475 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E)-but-2-enoyl-[acp] + NADH + H+→a butanoyl-[acp] + NAD+ (EC 1.3.1.9)
QEN71_RS06165 N.D.
QEN71_RS13540 +0.2
QEN71_RS30430 +0.6
QEN71_RS30525 +0.1
Beta-ketoacyl-acyl-carrier-protein synthase II:
a butanoyl-[acp] + a malonyl-[acp] + H+→a 3-oxohexanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
QEN71_RS03855 +0.6
QEN71_RS03870 +0.4
QEN71_RS03875 +0.3
QEN71_RS04565 N.D.
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxohexanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxyhexanoyl-[acp] + NADP+ (EC 1.1.1.100)
QEN71_RS01840 -0.1
QEN71_RS02665 -0.1
QEN71_RS02810 +0.1
QEN71_RS03865 +0.8
QEN71_RS04555 N.D.
QEN71_RS07495 -0.4
QEN71_RS08210 -0.3
QEN71_RS08280 +0.6
QEN71_RS10120 +0.4
QEN71_RS11605 +0.1
QEN71_RS12650 -2.5
QEN71_RS12790 +0.1
QEN71_RS13180 +0.2
QEN71_RS15615 +0.0
QEN71_RS15890 +0.2
QEN71_RS15970 N.D.
QEN71_RS16910 -0.5
QEN71_RS16930 N.D.
QEN71_RS18940 +0.1
QEN71_RS19320 +0.2
QEN71_RS19875 +0.2
QEN71_RS22470 +0.1
QEN71_RS22960 -0.0
QEN71_RS24385 N.D.
QEN71_RS24930 +0.1
QEN71_RS25895 +0.2
QEN71_RS27100 +0.2
QEN71_RS29765 +0.4
QEN71_RS30005 -0.5
QEN71_RS30200 +0.3
QEN71_RS30445 +0.0
QEN71_RS31020 +0.2
QEN71_RS31395 +0.2
QEN71_RS32355 +0.1
QEN71_RS32915 +0.0
QEN71_RS33390 -0.1
QEN71_RS33420 +0.0
QEN71_RS33735 +0.1
QEN71_RS33860 N.D.
QEN71_RS34325 +0.4
QEN71_RS34445 -0.7
QEN71_RS35630 -0.1
QEN71_RS36135 N.D.
QEN71_RS36540 -0.1
QEN71_RS36910 -0.2
QEN71_RS37725 -0.0
QEN71_RS38560 -0.1
QEN71_RS38920 -0.1
QEN71_RS39090 +0.4
QEN71_RS39175 -0.4
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxyhexanoyl-[acp]→a (2E)-hex-2-enoyl-[acp] + H2O (EC 4.2.1.59)
QEN71_RS06475 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E)-hex-2-enoyl-[acp] + NADH + H+→a hexanoyl-[acp] + NAD+ (EC 1.3.1.9)
QEN71_RS06165 N.D.
QEN71_RS13540 +0.2
QEN71_RS30430 +0.6
QEN71_RS30525 +0.1
Beta-ketoacyl-acyl-carrier-protein synthase II:
a hexanoyl-[acp] + a malonyl-[acp] + H+→a 3-oxooctanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
QEN71_RS03855 +0.6
QEN71_RS03870 +0.4
QEN71_RS03875 +0.3
QEN71_RS04565 N.D.
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxooctanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxyoctanoyl-[acp] + NADP+ (EC 1.1.1.100)
QEN71_RS01840 -0.1
QEN71_RS02665 -0.1
QEN71_RS02810 +0.1
QEN71_RS03865 +0.8
QEN71_RS04555 N.D.
QEN71_RS07495 -0.4
QEN71_RS08210 -0.3
QEN71_RS08280 +0.6
QEN71_RS10120 +0.4
QEN71_RS11605 +0.1
QEN71_RS12650 -2.5
QEN71_RS12790 +0.1
QEN71_RS13180 +0.2
QEN71_RS15615 +0.0
QEN71_RS15890 +0.2
QEN71_RS15970 N.D.
QEN71_RS16910 -0.5
QEN71_RS16930 N.D.
QEN71_RS18940 +0.1
QEN71_RS19320 +0.2
QEN71_RS19875 +0.2
QEN71_RS22470 +0.1
QEN71_RS22960 -0.0
QEN71_RS24385 N.D.
QEN71_RS24930 +0.1
QEN71_RS25895 +0.2
QEN71_RS27100 +0.2
QEN71_RS29765 +0.4
QEN71_RS30005 -0.5
QEN71_RS30200 +0.3
QEN71_RS30445 +0.0
QEN71_RS31020 +0.2
QEN71_RS31395 +0.2
QEN71_RS32355 +0.1
QEN71_RS32915 +0.0
QEN71_RS33390 -0.1
QEN71_RS33420 +0.0
QEN71_RS33735 +0.1
QEN71_RS33860 N.D.
QEN71_RS34325 +0.4
QEN71_RS34445 -0.7
QEN71_RS35630 -0.1
QEN71_RS36135 N.D.
QEN71_RS36540 -0.1
QEN71_RS36910 -0.2
QEN71_RS37725 -0.0
QEN71_RS38560 -0.1
QEN71_RS38920 -0.1
QEN71_RS39090 +0.4
QEN71_RS39175 -0.4
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxyoctanoyl-[acp]→a (2E)-oct-2-enoyl-[acp] + H2O (EC 4.2.1.59)
QEN71_RS06475 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E)-oct-2-enoyl-[acp] + NADH + H+→an octanoyl-[acp] + NAD+ (EC 1.3.1.9)
QEN71_RS06165 N.D.
QEN71_RS13540 +0.2
QEN71_RS30430 +0.6
QEN71_RS30525 +0.1
Beta-ketoacyl-acyl-carrier-protein synthase II:
an octanoyl-[acp] + a malonyl-[acp] + H+→a 3-oxodecanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
QEN71_RS03855 +0.6
QEN71_RS03870 +0.4
QEN71_RS03875 +0.3
QEN71_RS04565 N.D.
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxodecanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxydecanoyl-[acp] + NADP+ (EC 1.1.1.100)
QEN71_RS01840 -0.1
QEN71_RS02665 -0.1
QEN71_RS02810 +0.1
QEN71_RS03865 +0.8
QEN71_RS04555 N.D.
QEN71_RS07495 -0.4
QEN71_RS08210 -0.3
QEN71_RS08280 +0.6
QEN71_RS10120 +0.4
QEN71_RS11605 +0.1
QEN71_RS12650 -2.5
QEN71_RS12790 +0.1
QEN71_RS13180 +0.2
QEN71_RS15615 +0.0
QEN71_RS15890 +0.2
QEN71_RS15970 N.D.
QEN71_RS16910 -0.5
QEN71_RS16930 N.D.
QEN71_RS18940 +0.1
QEN71_RS19320 +0.2
QEN71_RS19875 +0.2
QEN71_RS22470 +0.1
QEN71_RS22960 -0.0
QEN71_RS24385 N.D.
QEN71_RS24930 +0.1
QEN71_RS25895 +0.2
QEN71_RS27100 +0.2
QEN71_RS29765 +0.4
QEN71_RS30005 -0.5
QEN71_RS30200 +0.3
QEN71_RS30445 +0.0
QEN71_RS31020 +0.2
QEN71_RS31395 +0.2
QEN71_RS32355 +0.1
QEN71_RS32915 +0.0
QEN71_RS33390 -0.1
QEN71_RS33420 +0.0
QEN71_RS33735 +0.1
QEN71_RS33860 N.D.
QEN71_RS34325 +0.4
QEN71_RS34445 -0.7
QEN71_RS35630 -0.1
QEN71_RS36135 N.D.
QEN71_RS36540 -0.1
QEN71_RS36910 -0.2
QEN71_RS37725 -0.0
QEN71_RS38560 -0.1
QEN71_RS38920 -0.1
QEN71_RS39090 +0.4
QEN71_RS39175 -0.4
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxydecanoyl-[acp]→a (2E)-dec-2-enoyl-[acp] + H2O (EC 4.2.1.59)
QEN71_RS06475 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E)-dec-2-enoyl-[acp] + NADH + H+→a decanoyl-[acp] + NAD+ (EC 1.3.1.9)
QEN71_RS06165 N.D.
QEN71_RS13540 +0.2
QEN71_RS30430 +0.6
QEN71_RS30525 +0.1
Beta-ketoacyl-acyl-carrier-protein synthase II:
a decanoyl-[acp] + a malonyl-[acp] + H+→a 3-oxododecanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
QEN71_RS03855 +0.6
QEN71_RS03870 +0.4
QEN71_RS03875 +0.3
QEN71_RS04565 N.D.
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxododecanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxydodecanoyl-[acp] + NADP+ (EC 1.1.1.100)
QEN71_RS01840 -0.1
QEN71_RS02665 -0.1
QEN71_RS02810 +0.1
QEN71_RS03865 +0.8
QEN71_RS04555 N.D.
QEN71_RS07495 -0.4
QEN71_RS08210 -0.3
QEN71_RS08280 +0.6
QEN71_RS10120 +0.4
QEN71_RS11605 +0.1
QEN71_RS12650 -2.5
QEN71_RS12790 +0.1
QEN71_RS13180 +0.2
QEN71_RS15615 +0.0
QEN71_RS15890 +0.2
QEN71_RS15970 N.D.
QEN71_RS16910 -0.5
QEN71_RS16930 N.D.
QEN71_RS18940 +0.1
QEN71_RS19320 +0.2
QEN71_RS19875 +0.2
QEN71_RS22470 +0.1
QEN71_RS22960 -0.0
QEN71_RS24385 N.D.
QEN71_RS24930 +0.1
QEN71_RS25895 +0.2
QEN71_RS27100 +0.2
QEN71_RS29765 +0.4
QEN71_RS30005 -0.5
QEN71_RS30200 +0.3
QEN71_RS30445 +0.0
QEN71_RS31020 +0.2
QEN71_RS31395 +0.2
QEN71_RS32355 +0.1
QEN71_RS32915 +0.0
QEN71_RS33390 -0.1
QEN71_RS33420 +0.0
QEN71_RS33735 +0.1
QEN71_RS33860 N.D.
QEN71_RS34325 +0.4
QEN71_RS34445 -0.7
QEN71_RS35630 -0.1
QEN71_RS36135 N.D.
QEN71_RS36540 -0.1
QEN71_RS36910 -0.2
QEN71_RS37725 -0.0
QEN71_RS38560 -0.1
QEN71_RS38920 -0.1
QEN71_RS39090 +0.4
QEN71_RS39175 -0.4
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxydodecanoyl-[acp]→a (2E)-dodec-2-enoyl-[acp] + H2O (EC 4.2.1.59)
QEN71_RS06475 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E)-dodec-2-enoyl-[acp] + NADH + H+→a dodecanoyl-[acp] + NAD+ (EC 1.3.1.9)
QEN71_RS06165 N.D.
QEN71_RS13540 +0.2
QEN71_RS30430 +0.6
QEN71_RS30525 +0.1
Dodecanoyl-[acyl-carrier-protein] hydrolase:
a dodecanoyl-[acp][nil] + H2O[nil]→laurate[nil] + a soluble [acyl-carrier protein][nil] + H+[nil] (EC 3.1.2.21)
No genes
Beta-ketoacyl-acyl-carrier-protein synthase II:
a dodecanoyl-[acp] + a malonyl-[acp] + H+→a 3-oxotetradecanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
QEN71_RS03855 +0.6
QEN71_RS03870 +0.4
QEN71_RS03875 +0.3
QEN71_RS04565 N.D.
Butyrate--CoA ligase:
laurate + ATP + coenzyme A→lauroyl-CoA + AMP + diphosphate (EC 6.2.1.2; 6.2.1.3)
QEN71_RS22975 -0.2
QEN71_RS27455 +0.1
QEN71_RS29275 -0.0
QEN71_RS37010 -0.0
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxotetradecanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxytetradecanoyl-[acp] + NADP+ (EC 1.1.1.100)
QEN71_RS01840 -0.1
QEN71_RS02665 -0.1
QEN71_RS02810 +0.1
QEN71_RS03865 +0.8
QEN71_RS04555 N.D.
QEN71_RS07495 -0.4
QEN71_RS08210 -0.3
QEN71_RS08280 +0.6
QEN71_RS10120 +0.4
QEN71_RS11605 +0.1
QEN71_RS12650 -2.5
QEN71_RS12790 +0.1
QEN71_RS13180 +0.2
QEN71_RS15615 +0.0
QEN71_RS15890 +0.2
QEN71_RS15970 N.D.
QEN71_RS16910 -0.5
QEN71_RS16930 N.D.
QEN71_RS18940 +0.1
QEN71_RS19320 +0.2
QEN71_RS19875 +0.2
QEN71_RS22470 +0.1
QEN71_RS22960 -0.0
QEN71_RS24385 N.D.
QEN71_RS24930 +0.1
QEN71_RS25895 +0.2
QEN71_RS27100 +0.2
QEN71_RS29765 +0.4
QEN71_RS30005 -0.5
QEN71_RS30200 +0.3
QEN71_RS30445 +0.0
QEN71_RS31020 +0.2
QEN71_RS31395 +0.2
QEN71_RS32355 +0.1
QEN71_RS32915 +0.0
QEN71_RS33390 -0.1
QEN71_RS33420 +0.0
QEN71_RS33735 +0.1
QEN71_RS33860 N.D.
QEN71_RS34325 +0.4
QEN71_RS34445 -0.7
QEN71_RS35630 -0.1
QEN71_RS36135 N.D.
QEN71_RS36540 -0.1
QEN71_RS36910 -0.2
QEN71_RS37725 -0.0
QEN71_RS38560 -0.1
QEN71_RS38920 -0.1
QEN71_RS39090 +0.4
QEN71_RS39175 -0.4
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxytetradecanoyl-[acp]→a (2E)-tetradec-2-enoyl-[acp] + H2O (EC 4.2.1.59)
QEN71_RS06475 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E)-tetradec-2-enoyl-[acp] + NADH + H+→a myristoyl-[acp] + NAD+ (EC 1.3.1.9)
QEN71_RS06165 N.D.
QEN71_RS13540 +0.2
QEN71_RS30430 +0.6
QEN71_RS30525 +0.1
Beta-ketoacyl-acyl-carrier-protein synthase II:
a myristoyl-[acp] + a malonyl-[acp] + H+→a 3-oxohexadecanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
QEN71_RS03855 +0.6
QEN71_RS03870 +0.4
QEN71_RS03875 +0.3
QEN71_RS04565 N.D.
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxohexadecanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxyhexadecanoyl-[acp] + NADP+ (EC 1.1.1.100)
QEN71_RS01840 -0.1
QEN71_RS02665 -0.1
QEN71_RS02810 +0.1
QEN71_RS03865 +0.8
QEN71_RS04555 N.D.
QEN71_RS07495 -0.4
QEN71_RS08210 -0.3
QEN71_RS08280 +0.6
QEN71_RS10120 +0.4
QEN71_RS11605 +0.1
QEN71_RS12650 -2.5
QEN71_RS12790 +0.1
QEN71_RS13180 +0.2
QEN71_RS15615 +0.0
QEN71_RS15890 +0.2
QEN71_RS15970 N.D.
QEN71_RS16910 -0.5
QEN71_RS16930 N.D.
QEN71_RS18940 +0.1
QEN71_RS19320 +0.2
QEN71_RS19875 +0.2
QEN71_RS22470 +0.1
QEN71_RS22960 -0.0
QEN71_RS24385 N.D.
QEN71_RS24930 +0.1
QEN71_RS25895 +0.2
QEN71_RS27100 +0.2
QEN71_RS29765 +0.4
QEN71_RS30005 -0.5
QEN71_RS30200 +0.3
QEN71_RS30445 +0.0
QEN71_RS31020 +0.2
QEN71_RS31395 +0.2
QEN71_RS32355 +0.1
QEN71_RS32915 +0.0
QEN71_RS33390 -0.1
QEN71_RS33420 +0.0
QEN71_RS33735 +0.1
QEN71_RS33860 N.D.
QEN71_RS34325 +0.4
QEN71_RS34445 -0.7
QEN71_RS35630 -0.1
QEN71_RS36135 N.D.
QEN71_RS36540 -0.1
QEN71_RS36910 -0.2
QEN71_RS37725 -0.0
QEN71_RS38560 -0.1
QEN71_RS38920 -0.1
QEN71_RS39090 +0.4
QEN71_RS39175 -0.4
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxyhexadecanoyl-[acp]→a (2E)-hexadec-2-enoyl-[acp] + H2O (EC 4.2.1.59)
QEN71_RS06475 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E)-hexadec-2-enoyl-[acp] + NADH + H+→a palmitoyl-[acp] + NAD+ (EC 1.3.1.9)
QEN71_RS06165 N.D.
QEN71_RS13540 +0.2
QEN71_RS30430 +0.6
QEN71_RS30525 +0.1
Oleoyl-[acyl-carrier-protein] hydrolase:
a palmitoyl-[acp] + H2O→palmitate + a soluble [acyl-carrier protein] + H+ (EC 3.1.2.14)
No genes
Long-chain-fatty-acid--CoA ligase:
palmitate + ATP + coenzyme A→palmitoyl-CoA + AMP + diphosphate (EC 6.2.1.3)
QEN71_RS22975 -0.2
QEN71_RS27455 +0.1
QEN71_RS29275 -0.0
QEN71_RS37010 -0.0

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information