MetaCyc Pathway: superpathway of L-serine and glycine biosynthesis I in Paraburkholderia sabiae LMG 24235

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Reactions and Genes L-Leucine (C)
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Phosphoglycerate dehydrogenase:
3-phospho-D-glycerate + NAD+→3-phosphooxypyruvate + NADH + H+ (EC 1.1.1.95)
QEN71_RS00125 -0.2
QEN71_RS01065 -1.7
QEN71_RS08140 +0.1
QEN71_RS12095 +0.2
QEN71_RS32025 -0.2
QEN71_RS39040 -0.0
Phosphoserine transaminase (in reverse):
3-phosphooxypyruvate + L-glutamate→O-phospho-L-serine + 2-oxoglutarate (EC 2.6.1.52)
QEN71_RS04065 -3.1
Phosphoserine phosphatase:
O-phospho-L-serine + H2O→L-serine + phosphate (EC 3.1.3.3)
QEN71_RS00870 -0.5
QEN71_RS22160 -2.8
QEN71_RS26460 -3.3
Glycine hydroxymethyltransferase:
L-serine + a tetrahydrofolate→glycine + a 5,10-methylenetetrahydrofolate + H2O (EC 2.1.2.1)
QEN71_RS08310 -0.1
QEN71_RS11055 +0.1
QEN71_RS26235 -3.8
QEN71_RS33600 -0.4
QEN71_RS34010 -0.3
QEN71_RS34315 +0.2
QEN71_RS35520 -0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information