MetaCyc Pathway: superpathway of L-methionine biosynthesis (by sulfhydrylation) in Paraburkholderia sabiae LMG 24235

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Reactions and Genes Plant=Phaseolus_vulgaris; PlantTreatment=None; Sample=rhizosphere; GrowthSubstrate=0.5X_MS_agar; Collection=outgrowth_LB; Time=14_days
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Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→L-aspartate + 2-oxoglutarate (EC 2.6.1.1)
QEN71_RS00075 +0.1
QEN71_RS02890 -0.0
QEN71_RS03175 +0.1
QEN71_RS03275 +0.1
QEN71_RS06560 +0.2
QEN71_RS08880 +0.1
QEN71_RS10500 +0.1
QEN71_RS12205 -0.2
QEN71_RS12215 -0.5
QEN71_RS13030 -0.0
QEN71_RS17025 -0.0
QEN71_RS18160 -0.2
QEN71_RS18375 -0.4
QEN71_RS20720 +0.2
QEN71_RS21505 +0.2
QEN71_RS22410 -1.9
QEN71_RS23125 +0.1
QEN71_RS23470 -0.1
QEN71_RS24010 +0.0
QEN71_RS24645 -0.1
QEN71_RS30710 -0.0
QEN71_RS31640 +0.1
QEN71_RS32300 -0.4
QEN71_RS36905 +0.3
QEN71_RS38860 +0.1
QEN71_RS38900 +0.1
QEN71_RS38970 +0.4
Sulfate adenylyltransferase:
sulfate + ATP + H+→adenosine 5'-phosphosulfate + diphosphate (EC 2.7.7.4)
QEN71_RS25235 -3.9
QEN71_RS25240 -4.5
Adenylyl-sulfate kinase:
adenosine 5'-phosphosulfate + ATP→3'-phosphoadenylyl-sulfate + ADP + H+ (EC 2.7.1.25)
QEN71_RS25815 +0.4
QEN71_RS42090 +0.2
Aspartate kinase:
L-aspartate + ATP→L-aspartyl-4-phosphate + ADP (EC 2.7.2.4)
QEN71_RS06150 -5.0
Phosphoadenylyl-sulfate reductase (thioredoxin) (in reverse):
3'-phosphoadenylyl-sulfate + a reduced thioredoxin→sulfite + adenosine 3',5'-bisphosphate + an oxidized thioredoxin + 2 H+ (EC 1.8.4.8)
QEN71_RS25245 -3.9
Aspartate-semialdehyde dehydrogenase (in reverse):
L-aspartyl-4-phosphate + NADPH + H+→L-aspartate 4-semialdehyde + NADP+ + phosphate (EC 1.2.1.11)
QEN71_RS17625 N.D.
Homoserine dehydrogenase (in reverse):
L-aspartate 4-semialdehyde + NAD(P)H + H+→L-homoserine + NAD(P)+ (EC 1.1.1.3)
QEN71_RS22405 -6.4
Sulfite reductase (NADPH) (in reverse):
sulfite + 3 NADPH + 5 H+→hydrogen sulfide + 3 NADP+ + 3 H2O (EC 1.8.1.2)
QEN71_RS25255 -4.3
QEN71_RS36875 -0.1
Homoserine O-acetyltransferase:
L-homoserine + acetyl-CoA→O-acetyl-L-homoserine + coenzyme A (EC 2.3.1.31)
QEN71_RS00285 -1.0
QEN71_RS00290 -5.1
QEN71_RS16300 -0.1
QEN71_RS42530 -0.5
O-acetylhomoserine aminocarboxypropyltransferase:
O-acetyl-L-homoserine + hydrogen sulfide→L-homocysteine + acetate + H+ (EC 2.5.1.49)
QEN71_RS05200 +0.2
QEN71_RS17685 +0.1
QEN71_RS23590 +0.3
QEN71_RS33705 -1.1
QEN71_RS42510 +0.2
5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase:
L-homocysteine + 5-methyltetrahydropteroyl tri-L-glutamate→L-methionine + tetrahydropteroyl tri-L-glutamate (EC 2.1.1.14)
QEN71_RS19725 -0.8
Methionine synthase:
L-homocysteine + a 5-methyltetrahydrofolate→L-methionine + a tetrahydrofolate (EC 2.1.1.13)
QEN71_RS01190 +0.0
QEN71_RS01195 -0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information