MetaCyc Pathway: coumarin biosynthesis (via 2-coumarate) in Bacteroides ovatus ATCC 8483

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Reactions and Genes b-Glucan from Beet (1,2-b-Glucan) 2.5 mg/mL (C)
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Trans-cinnamate 2-monooxygenase:
trans-cinnamate + NADPH + dioxygen + H+→trans-2-coumarate + NADP+ + H2O (EC 1.14.13.14)
No genes
2-coumarate O-beta-glucosyltransferase:
trans-2-coumarate + UDP-α-D-glucose→trans-β-D-glucosyl-2-hydroxycinnamate + H+ + UDP (EC 2.4.1.114)
No genes
trans-β-D-glucosyl-2-hydroxycinnamate→cis-β-D-glucosyl-2-hydroxycinnamate
No genes
Beta-glucosidase:
cis-β-D-glucosyl-2-hydroxycinnamate + H2O→cis-2-coumarate + D-glucopyranose (EC 3.2.1.21)
BACOVA_00260 -0.0
BACOVA_00426 -0.0
BACOVA_00427 -0.2
BACOVA_00428 -0.2
BACOVA_00625 +0.2
BACOVA_00946 -0.1
BACOVA_02109 -0.2
BACOVA_02110 +0.1
BACOVA_02644 +0.0
BACOVA_02659 -0.1
BACOVA_02738 +0.0
BACOVA_02745 -0.1
BACOVA_02753 -0.2
BACOVA_02769 -0.0
BACOVA_02958 -0.0
BACOVA_03379 +0.1
BACOVA_03380 -1.8
BACOVA_03399 -0.0
BACOVA_03419 -0.1
BACOVA_03560 +0.0
BACOVA_04181 -0.0
BACOVA_04927 +0.2
BACOVA_05181 -0.1
BACOVA_05565 +0.0
cis-2-coumarate + H+→coumarin + H2O (spontaneous)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information