MetaCyc Pathway: superpathway of L-aspartate and L-asparagine biosynthesis in Escherichia coli HS(pFamp)R (ATCC 700891)

Add experiment(s):


Reactions and Genes lim MOI1
remove
Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→L-aspartate + 2-oxoglutarate (EC 2.6.1.1)
OHPLBJKB_02738 -1.5
OHPLBJKB_03726 +0.2
Aspartate ammonia-lyase (in reverse):
fumarate + ammonium→L-aspartate (EC 4.3.1.1)
OHPLBJKB_03904 -1.4
Aspartate--ammonia ligase:
L-aspartate + ammonium + ATP→L-asparagine + AMP + diphosphate + H+ (EC 6.3.1.1)
OHPLBJKB_03042 +0.0
OHPLBJKB_04309 +0.1
Asparaginase:
L-asparagine + H2O→L-aspartate + ammonium (EC 3.5.1.1; 3.5.1.38; 3.5.5.4)
OHPLBJKB_00759 +0.0
OHPLBJKB_01965 -0.1

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information